基于“卫气稽留”理论论治寻常型银屑病
Treatment of Psoriasis Vulgaris Based on the Theory of “Wei-Qi Retention”
摘要: 银屑病作为临床难治性疾病之一,其发病机制复杂且缠绵难愈。本文以《黄帝内经》“卫气稽留”理论为根基,系统阐释其从红斑迸发、斑块固着到燥屑脱落的全程演变规律,其病机可归结为肺脾肾亏虚导致的卫气稽留,并在此基础上进一步发展为血热,血瘀,血燥三大病理改变。针对这一复杂病程演变并结合临床实际,提出了七种辨证治法,即辛凉轻宣以散卫热,凉血散血以清血热、养血润燥以生卫源、活血祛瘀以疏卫道、补肺益气以行卫气、健脾化湿以澄卫源、补肾纳气以固卫根,如此方能营卫得源、清浊得分,卫气得行,血脉得通、卫行得畅,身无邪扰、内外皆安。本文通过整合古籍文献与现代医学研究,不仅为寻常型银屑病的中医药治疗提供了理论依据,也为临床实践开拓了新的理论支撑与实践路径。“卫气稽留”理论来源于《黄帝内经》,基于“卫气稽留”理论,结合现代医学对寻常型银屑病的描述,认识到根据“卫气稽留”理论所描述的病理状态与寻常型银屑病的分期相契合,据此提出基于“卫气稽留”理论论治寻常型银屑病,旨在为中医药治疗寻常型银屑病提供新的思路。
Abstract: Psoriasis, a clinically refractory disease characterized by complex pathogenesis and protracted course, is systematically elucidated in this paper through the theoretical framework of “wei-qi retention” from the Huangdi Neijing. The study clarifies its holistic evolutionary pattern from erythema eruption and plaque consolidation to xerotic desquamation, attributing the pathogenesis to constitutional deficiencies of lung, spleen, and kidney leading to wei-qi retention, which further develops into three major pathological transformations: blood-heat, blood-stasis, and blood-dryness. Addressing this complex pathological progression and integrating clinical practice, seven syndrome-differentiated therapeutic strategies are proposed: (1) dispersing Wei-heat through pungent-cool exterior-releasing methods; (2) clearing blood-heat via cooling and dispersing blood; (3) nourishing blood and moistening dryness to regenerate wei-qi sources; (4) promoting blood circulation and removing stasis to unblock wei-qi pathways; (5) reinforcing lung and benefiting qi to regulate wei-qi movement; (6) strengthening spleen and resolving dampness to purify wei-qi origins; and (7) tonifying kidney and anchoring qi to consolidate wei-qi roots. These approaches aim to restore the origin of ying-qi and wei-qi, differentiate clarity from turbidity, ensure smooth circulation of wei-qi and blood vessels, and ultimately achieve internal-external homeostasis free from pathogenic disturbances. By integrating classical medical literature with modern research, this study not only provides theoretical foundations for traditional Chinese medicine (TCM) treatment of psoriasis vulgaris but also opens new theoretical and practical pathways for clinical practice. The “wei-qi retention” theory, rooted in the Huangdi Neijing, demonstrates remarkable alignment with modern medical descriptions of psoriasis vulgaris staging. This paper proposes a TCM therapeutic approach for psoriasis vulgaris based on the “wei-qi retention” theory, aiming to offer novel perspectives for TCM treatment of this condition.
文章引用:李昊, 刘拥军. 基于“卫气稽留”理论论治寻常型银屑病[J]. 临床医学进展, 2026, 16(4): 3333-3339. https://doi.org/10.12677/acm.2026.1641595

参考文献

[1] 丁元庆. 《内经》营卫理论回顾[J]. 山东中医药大学学报, 2017, 41(1): 3-7.
[2] 高颖, 叶欣, 向句一, 夏婷, 曾进浩. 基于“卫气稽留”论治化疗后中性粒细胞减少症[J]. 世界科学技术-中医药现代化, 2022, 24(9): 3638-3643.
[3] 曹一钦, 文昌晖, 王秀琳, 张玲丽, 贾敏, 李斌. 基于网络药理学的金银花-连翘药对干预银屑病的分子机制[J]. 西部中医药, 2022, 35(11): 8-15.
[4] 胡淑雅, 刘爱民, 冉铭娟, 侯舒川. 犀角地黄汤及其单味药有效成分治疗银屑病研究进展[J/OL]. 辽宁中医药大学学报, 2025: 1-16.
https://link.cnki.net/urlid/21.1543.R.20251126.1434.007, 2026-04-12.
[5] 陈嘉, 张晴, 安月鹏, 杨素清. 犀角地黄汤治疗银屑病的研究进展[J]. 中国医药导报, 2025, 22(29): 107-111.
[6] 胡梦娇, 张慧杰. 基于网络药理学和分子对接的活血化瘀药对当归-红花调节IL-17信号通路治疗银屑病作用机制研究[J]. 中国中西医结合皮肤性病学杂志, 2025, 24(2): 112-119.
[7] 俞鹏飞, 薛凯元, 林立, 杨婧雯, 安月鹏, 袁锐, 王姗姗, 杨素清. 基于网络药理学及分子对接分析当归-川芎药对治疗银屑病的作用机制[J]. 中国医院用药评价与分析, 2024, 24(8): 910-914.
[8] 王栩芮, 李明玥, 庞尧斌, 陈安婧, 刘娥, 赵谊佳, 郭静. 当归饮子治疗寻常型银屑病的药理实验与分子生物学机制[J]. 世界中医药, 2025, 20(14): 2432-2440.
[9] 李红霞, 赵泽鑫, 卢忠, 罗德苹, 陈雨佳, 管连城, 杨凡, 李福伦. 黄芪对银屑病小鼠中性粒细胞VDR表达及NETs形成的影响[J/OL]. 中华中医药学刊, 2025: 1-13.
https://link.cnki.net/urlid/21.1546.R.20251011.1009.002, 2026-04-12.
[10] 王雾. 人参皂苷CK对咪喹莫特诱导的小鼠银屑病的治疗作用[D]: [硕士学位论文]. 合肥: 安徽医科大学, 2021.
[11] 叶泽婷. 参苓白术胶囊对脾虚湿阻证银屑病大鼠的作用机制及药效物质基础研究[D]: [硕士学位论文]. 广州: 广州中医药大学, 2024.
[12] 郑树茂, 王华, 王淑惠, 雷明君, 解朋云. 茯苓酸对银屑病小鼠皮损组织IRS-1/ERK1/2通路及角质形成细胞增殖的影响[J]. 中国老年学杂志, 2024, 44(9): 2138-2143.