柠檬果胶用于改善功能性便秘的疗效分析

Analysis of the Efficacy of Lemon Pectin in Improving Functional Constipation

摘要: 目的：初步探讨柠檬果胶用于改善功能性便秘(Functional Constipation, FC)的疗效分析。方法：本次研究采用自身前后对照的临床研究方法。选择2025-05至2025-11重庆市潼南区人民医院的30例被诊断为FC (罗马IV标准)的患者均给予柠檬果胶按一次10 g，一日3次规范治疗，分别收集研究对象食用柠檬果胶前基线治疗、食用柠檬果胶4周疗程结束时的便秘严重程度、单次排便时间、排便性状、排便困难评分、综合疗效、不良反应，对比分析食用柠檬果胶前后各指标动态变化。评价柠檬果胶的临床疗效、起效特点及安全性。结果：30例FC患者应用柠檬果胶后，患者治疗后排便评率、粪便性状、排便困难评分、单次排便时间均较基线显著改善(P < 0.05)；综合疗效痊愈、显效、有效共28例(93.33%)，无效2例(6.67%)，总有效率可观；仅5例(16.67%)出现轻微腹胀、恶心等不良反应，无严重不良事件发生。结论：柠檬果胶可有效改善FC患者的排便性状，且临床应用安全性良好，具有较高临床推广价值。

Abstract: Objective: A Preliminary Investigation into the Efficacy of Lemon Pectin in Alleviating Functional Constipation (FC). Methods: This study adopted a self-controlled clinical research method. Thirty patients diagnosed with FC (Rome IV criteria) at Chongqing Tongnan District People’s Hospital from May 2025 to November 2025 were given standardized treatment with lemon pectin (10 g once, three times daily). We collect separately the baseline treatment, constipation severity, single defecation time, stool consistency, defecation difficulty score, comprehensive efficacy, and adverse reactions of the subjects before consuming lemon pectin and at the end of the 4-week treatment course, compare the dynamic changes of various indicators before and after the intake of edible lemon pectin. We evaluate the clinical efficacy, onset characteristics, and safety of lemon pectin. Results: In 30 cases of FC treated with lemon pectin, patients showed significant improvements in defecation frequency, stool consistency, difficulty in defecation score, and single defecation time compared to baseline (P < 0.05). The comprehensive efficacy included 28 cases (93.33%) with cure, marked effectiveness, or effectiveness, and 2 cases (6.67%) with no effect, demonstrating a considerable overall effectiveness rate. Only 5 cases (16.67%) experienced mild adverse reactions such as bloating and nausea, with no occurrence of serious adverse events. Conclusion: Lemon pectin can effectively improve the bowel movement characteristics of patients with FC, and its clinical application has good safety, making it highly valuable for clinical promotion.