针刺疗法在神经性耳鸣治疗中的临床疗效与 作用机制研究进展
Research Progress on the Clinical Efficacy and Mechanism of Action of Acupuncture in the Treatment of Neurogenic Tinnitus
DOI: 10.12677/acm.2026.1641645, PDF,   
作者: 唐铭科:黑龙江省中医药科学院,黑龙江 哈尔滨;王 顺*:黑龙江中医药大学第二临床医学院,黑龙江 哈尔滨
关键词: 针刺神经性耳鸣研究进展作用机制Acupuncture Neurogenic Tinnitus Research Progress Mechanism of Action
摘要: 神经性耳鸣(neurogenic tinnitus, NT)是临床常见的耳科疾病,患者在无外界声源刺激时主观感知耳内或颅内有鸣响,该疾病发病率较高,且对患者的生活质量产生显著负面影响。本病好发于中老年人群,然而近年来在中青年群体中的患病率也呈现上升趋势。因其发病机制尚未完全阐明,现有西医治疗手段存在一定局限,且复发率较高。基于这一现状,针刺疗法凭借其良好疗效与较高安全性,日益成为NT治疗中重要的替代与补充方案。在中医理论指导下,针灸治疗策略不断丰富,有助于减轻耳鸣严重程度,改善整体治疗效果,并对患者身心健康的恢复具有积极意义。本文综述针刺在该疾病领域的临床应用现状及近年研究进展,归纳其疗效与独特优势,同时指出当前研究的局限之处,并对未来研究方向作出展望。
Abstract: Neurogenic tinnitus (NT) is a common clinical otologic disorder characterized by the subjective perception of ringing in the ears or head in the absence of external sound stimuli. This condition exhibits a high prevalence and significantly impacts patients’ quality of life. This condition predominantly affects middle-aged and elderly individuals, though its prevalence among younger adults has shown an upward trend in recent years. Due to its incomplete understanding of pathogenesis, existing Western medical treatments exhibit certain limitations and high recurrence rates. Against this backdrop, acupuncture therapy, with its favorable efficacy and high safety profile, has increasingly become an important alternative and complementary approach in treating neurogenic tinnitus. Guided by traditional Chinese medicine theory, acupuncture treatment strategies continue to evolve, helping to reduce tinnitus severity, improve overall therapeutic outcomes, and positively contribute to patients’ physical and mental recovery. This review summarizes the current clinical application of acupuncture in this field and recent research advances, outlines its efficacy and unique advantages, identifies limitations in current studies, and provides insights into future research directions.
文章引用:唐铭科, 王顺. 针刺疗法在神经性耳鸣治疗中的临床疗效与 作用机制研究进展[J]. 临床医学进展, 2026, 16(4): 3781-3788. https://doi.org/10.12677/acm.2026.1641645

参考文献

[1] Jarach, C.M., Lugo, A., Scala, M., van den Brandt, P.A., Cederroth, C.R., Odone, A., et al. (2022) Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-Analysis. JAMA Neurology, 79, 888-900. [Google Scholar] [CrossRef] [PubMed]
[2] 孙慧颖, 冯国栋, 高志强. 影响慢性主观性耳鸣严重程度的关键因素分析: 基于复杂网络分析的研究[J]. 临床耳鼻咽喉头颈外科杂志, 2021, 35(7): 586-592.
[3] Kleinjung, T., Peter, N., Schecklmann, M. and Langguth, B. (2024) The Current State of Tinnitus Diagnosis and Treatment: A Multidisciplinary Expert Perspective. Journal of the Association for Research in Otolaryngology, 25, 413-425. [Google Scholar] [CrossRef] [PubMed]
[4] 贺璐, 王国鹏, 彭哲, 等. 耳鸣临床应用指南[J]. 听力学及言语疾病杂志, 2015(2): 116-139.
[5] Kuzucu, I. and Karaca, O. (2020) Acupuncture Treatment in Patients with Chronic Subjective Tinnitus: A Prospective, Randomized Study. Medical Acupuncture, 32, 24-28. [Google Scholar] [CrossRef] [PubMed]
[6] 李成龙, 茅伟, 张利达, 等. “通督调神”法针刺治疗主观性耳鸣: 随机对照试验[J]. 中国针灸, 2024, 44(6): 648-652.
[7] 孔庆丽, 牛红月. 针刺肾关穴治疗青年神经性耳鸣32例[J]. 中国针灸, 2021, 41(11): 1260.
[8] 王成芳, 汪芸芸, 周名誉. 通元法针刺对肾精亏损型神经性耳鸣病人中医症候积分、THI评分及睡眠质量的影响[J]. 蚌埠医学院学报, 2023(7): 959-962.
[9] 宋琦, 李桂平. “三步通窍”法针灸治疗神经性耳鸣32例[J]. 中国针灸, 2023, 43(8): 904-906.
[10] 李成龙, 张利达, 韩为, 等. 不同灸量温针灸治疗主观性耳鸣的临床观察[J]. 上海针灸杂志, 2022, 41(3): 279-284.
[11] Wu, Q., Wang, J., Han, D., Hu, H. and Gao, H. (2023) Efficacy and Safety of Acupuncture and Moxibustion for Primary Tinnitus: A Systematic Review and Meta-Analysis. American Journal of Otolaryngology, 44, Article ID: 103821. [Google Scholar] [CrossRef] [PubMed]
[12] 孙振鹏, 万红棉. 苇管灸联合针刺治疗神经性耳鸣的疗效观察[J]. 上海针灸杂志, 2024(8): 836-840.
[13] 张沥丹. 雷火灸结合刺络放血治疗神经性耳鸣(气滞血瘀型)的临床研究[D]: [硕士学位论文]. 长春: 长春中医药大学, 2024.
[14] Zhang, R., Lao, L., Ren, K. and Berman, B.M. (2014) Mechanisms of Acupuncture-Electroacupuncture on Persistent Pain. Anesthesiology, 120, 482-503. [Google Scholar] [CrossRef] [PubMed]
[15] Han, J. (2003) Acupuncture: Neuropeptide Release Produced by Electrical Stimulation of Different Frequencies. Trends in Neurosciences, 26, 17-22. [Google Scholar] [CrossRef] [PubMed]
[16] Llinás, R.R., Ribary, U., Jeanmonod, D., Kronberg, E. and Mitra, P.P. (1999) Thalamocortical Dysrhythmia: A Neurological and Neuropsychiatric Syndrome Characterized by Magnetoencephalography. Proceedings of the National Academy of Sciences, 96, 15222-15227. [Google Scholar] [CrossRef] [PubMed]
[17] Li, B., Zhao, Q., Du, Y., Li, X., Li, Z., Meng, X., et al. (2022) Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine, 2022, Article ID: 3740856. [Google Scholar] [CrossRef] [PubMed]
[18] 武瑾慧, 高山. 电针辅治神经性耳鸣临床观察[J]. 实用中医药杂志, 2023, 39(1): 132-135.
[19] 江训伟. 电针耳三穴联合聪耳通窃汤辅治神经性耳鸣临床观察[J]. 实用中医药杂志, 2021, 37(8): 1375-1377.
[20] Guo, Y., Ho, L.F., Chen, L., et al. (2023) Electroacupuncture with or without Combined Warm Needling for Tinnitus: Study Protocol for a Randomized, Waitlist-Controlled Trial. Medicine, 102, e34315. [Google Scholar] [CrossRef
[21] Kim, S.H., Kim, D., Lee, J., Lee, S.K., Kang, H.J. and Yeo, S.G. (2021) Review of Pharmacotherapy for Tinnitus. Healthcare, 9, Article No. 779. [Google Scholar] [CrossRef] [PubMed]
[22] Khodorova, A., Meissner, K., Leeson, S. and Strichartz, G.R. (2001) Lidocaine Selectively Blocks Abnormal Impulses Arising from Noninactivating Na Channels. Muscle & Nerve, 24, 634-647. [Google Scholar] [CrossRef] [PubMed]
[23] 邹冰. 利多卡因穴位注射治疗主观性耳鸣疗效观察[J]. 广西中医学院学报, 2006, 9(1): 32-33.
[24] Ren, J., Fu, L., Nile, S.H., Zhang, J. and Kai, G. (2019) Salvia Miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications. Frontiers in Pharmacology, 10, Article No. 753. [Google Scholar] [CrossRef] [PubMed]
[25] 李亮, 杨志英, 朱全红. 针刺率谷穴配合穴位注射治疗神经性耳鸣疗效观察[J]. 上海针灸杂志, 2020, 39(5): 559-564.
[26] Liu, Y., Gao, J., Peng, M., Meng, H., Ma, H., Cai, P., et al. (2018) A Review on Central Nervous System Effects of Gastrodin. Frontiers in Pharmacology, 9, Article No. 24. [Google Scholar] [CrossRef] [PubMed]
[27] 罗扬拓, 冯帅, 姜学钧, 等. 听觉中枢可塑性与耳鸣发生机制的研究进展[J]. 临床耳鼻咽喉头颈外科杂志, 2021, 35(11): 91-95.
[28] Wang, X., Zhang, B., Li, X., Liu, X., Wang, S., Xie, Y., et al. (2021) Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain. Frontiers in Pharmacology, 12, Article ID: 744663. [Google Scholar] [CrossRef] [PubMed]
[29] Jiang, J.F., et al. (2016) Analysis of Factors Influencing Moxibustion Efficacy by Affecting Heat-Activated Transient Receptor Potential Vanilloid Channels. Journal of Traditional Chinese Medicine, 36, 255-260. [Google Scholar] [CrossRef] [PubMed]
[30] Ho, L.F., Guo, Y., Chen, L., Fung, H., Mak, W.Y., Cheung, S.C., et al. (2025) Efficacy and Safety of Electroacupuncture and Electroacupuncture Combined with Warm Needling for Subjective Tinnitus: A Multicenter, Three-Arm Randomized Controlled Trial. Complementary Therapies in Medicine, 91, Article ID: 103191. [Google Scholar] [CrossRef] [PubMed]
[31] Ji, L., Zhang, H., Wang, L., Yin, Z., Cen, J. and Guo, Y. (2023) Network Meta-Analysis of Acupuncture for Tinnitus. Medicine, 102, e35019. [Google Scholar] [CrossRef] [PubMed]
[32] 马莉, 陈玉. 捏鼻鼓气联合温针灸治疗神经性耳鸣的临床研究[J]. 中医药导报, 2020, 26(14): 77-79.
[33] 周冰雪, 老锦雄. 蜂针联合温针灸治疗神经性耳鸣的临床观察[J]. 广州中医药大学学报, 2019, 36(11): 1749-1752.
[34] 宋春侠, 刘经州, 徐立伟, 等. 针药并用治疗痰瘀阻络型神经性耳鸣的疗效观察[J]. 上海针灸杂志, 2020, 39(5): 555-558.
[35] 孙献峰. 针药结合治疗肾精亏虚型神经性耳鸣的疗效观察[J]. 中国中医药科技, 2025(3): 551-553.
[36] 任小青, 陈晓玲, 董鹏飞. 小柴胡汤加减联合针刺治疗神经性耳鸣临床观察[J]. 实用中医药杂志, 2024, 40(3): 433-435.
[37] 郑乃祯. “发蒙针法”联合耳穴揿针治疗肾精亏虚型原发性耳鸣的临床疗效观察[D]: [硕士学位论文]. 福州: 福建中医药大学, 2025.
[38] 陈文鑫, 武沛欣, 刘冰冰, 等. 磁圆梅针联合针刺对穴翳风-听会治疗神经性耳鸣的临床研究[J]. 山西中医药大学学报, 2025(6): 649-654.