抑郁症躯体化的机制与干预进展
Advances in the Mechanisms and Interventions of Somatization in Depression
DOI: 10.12677/acm.2026.1641647, PDF,    科研立项经费支持
作者: 杨芯颜, 杜 莲*:重庆医科大学附属第一医院,重庆
关键词: 抑郁症躯体化述情障碍心理动力学Depression Somatization Alexithymia Psychodynamics
摘要: 抑郁症的躯体化表现广泛且显著影响诊治与预后,但其机制与干预缺乏系统整合。本文基于既往心理与生物学证据,提出“情绪加工与防御–认知维持–神经生理放大与固化”的三级机制模型,认为抑郁症躯体化症状是由情绪加工障碍与防御机制起源,经反刍与灾难化认知维持,并在长期应激下被神经生理放大和固化。据此提出以分级、分阶为核心的机制导向的干预策略,为抑郁症躯体化症状的精准治疗提供理论依据。
Abstract: Somatic manifestations of depression are prevalent and exert substantial impact on clinical assessment, treatment, and prognosis; however, their underlying mechanisms and corresponding interventions remain insufficiently integrated. Drawing on existing psychological and biological evidence, this review proposes a three-level mechanistic model comprising emotional processing and defense, cognitive maintenance, and neurophysiological amplification and consolidation. Within this framework, somatic symptoms in depression are conceptualized as originating from impairments in emotional processing and maladaptive defense mechanisms, sustained by rumination and catastrophizing cognitions, and subsequently amplified and stabilized through neurophysiological dysregulation under chronic stress. On this basis, a mechanism-oriented intervention strategy emphasizing graded and staged matching is proposed, providing a theoretical foundation for precision treatment of somatic symptoms in depression.
文章引用:杨芯颜, 杜莲. 抑郁症躯体化的机制与干预进展[J]. 临床医学进展, 2026, 16(4): 3797-3808. https://doi.org/10.12677/acm.2026.1641647

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