千金苇茎汤化裁联合穴位贴敷对老年重症肺炎患者临床分析
Clinical Efficacy Analysis of Modified Qianjin Weijing Decoction Combined with Acupoint Application in Elderly Patients with Severe Pneumonia
摘要: 目的:本研究通过回顾性对比试验,评价千金苇茎汤化裁联合穴位贴敷对老年重症肺炎患者的临床效果,分析其对呼吸功能、炎症反应、凝血功能及复发率的影响,为中西医结合治疗提供循证依据。方法:选取2023年12月至2024年8月伊犁州奎屯医院呼吸科200例老年重症肺炎患者,随机分为对照组(n = 100)和观察组(n = 100)。对照组采用常规西医治疗,观察组加用千金苇茎汤化裁联合穴位贴敷。比较两组呼吸力学指标、炎症因子水平、血气指标、症状改善时间、凝血功能指标及复发率,采用SPSS 27.0软件分析,P < 0.05为差异有统计学意义。结果:两组基线特征无显著差异(P > 0.05)。观察组呼吸功能、炎症反应及氧合状态相关指标显著优于对照组(P < 0.05);症状改善时间缩短,凝血功能指标更优(P < 0.05);复发率显著低于对照组(P < 0.05)。结论:千金苇茎汤化裁联合穴位贴敷可改善老年重症肺炎患者呼吸功能、减轻炎症反应、提升氧合状态、缓解症状、改善凝血功能并降低复发率,为中西医结合治疗提供循证依据,为中医药现代化提供新思路。
Abstract: Objective: This study aims to evaluate the clinical efficacy of modified Qianjin Weijing Decoction combined with acupoint application in elderly patients with severe pneumonia through a retrospective controlled trial, analyze its effects on respiratory function, inflammatory response, coagulation function, and recurrence rate, and provide evidence-based basis for integrated traditional Chinese and Western medicine treatment. Methods: A total of 200 elderly patients with severe pneumonia admitted to the Department of Respiratory Medicine, Kuitun Hospital of Yili Prefecture from December 2023 to August 2024 were randomly divided into a control group (n = 100) and an observation group (n = 100). The control group received conventional Western medicine treatment, while the observation group was additionally given modified Qianjin Weijing Decoction combined with acupoint application. Respiratory mechanics indexes, inflammatory factor levels, blood gas indexes, symptom improvement time, coagulation function indexes, and recurrence rate were compared between the two groups. SPSS 27.0 software was used for statistical analysis, with P < 0.05 indicating statistically significant differences. Results: There were no significant differences in baseline characteristics between the two groups (P > 0.05). The observation group showed significantly better performance in respiratory function, inflammatory response, oxygenation status (P < 0.05), shorter symptom improvement time, better coagulation function indexes (P < 0.05), and a significantly lower recurrence rate (P < 0.05) compared with the control group. Conclusion: Modified Qianjin Weijing Decoction combined with acupoint application can improve respiratory function, reduce inflammatory response, enhance oxygenation status, relieve symptoms, improve coagulation function, and lower recurrence rate in elderly patients with severe pneumonia. It provides evidence-based support for integrated traditional Chinese and Western medicine treatment and new insights into the modernization of traditional Chinese medicine in clinical practice.
文章引用:李秀玲, 王二龙, 陈欣欣. 千金苇茎汤化裁联合穴位贴敷对老年重症肺炎患者临床分析[J]. 临床医学进展, 2026, 16(4): 5026-5034. https://doi.org/10.12677/acm.2026.1641775

参考文献

[1] 景文展, 刘民. 世界卫生组织应对新型冠状病毒肺炎的机制[J]. 中华流行病学杂志, 2020, 41(9): 1385-1389.
[2] 杜侠, 王伟, 张延玲, 等. 老年重症肺炎诊疗进展[J]. 中国医刊, 2021, 56(9): 942-946.
[3] 杨爱琴, 韩晓燕, 陈洁. 宣壅清肺汤治疗老年重症肺炎临床观察[J]. 辽宁中医杂志, 2024, 51(6): 74-77.
[4] Tang, H., Yuan, Z., Li, J., Wang, Q. and Fan, W. (2022) The Application of Ambroxol Hydrochloride Combined with Fiberoptic Bronchoscopy in Elderly Patients with Severe Pneumonia. Medicine, 101, e28535. [Google Scholar] [CrossRef] [PubMed]
[5] Zhang, P., Liu, B., Zhang, S., Chang, X., Zhang, L., Gu, D., et al. (2024) Clinical Application of Targeted Next-Generation Sequencing in Severe Pneumonia: A Retrospective Review. Critical Care, 28, Article No. 225. [Google Scholar] [CrossRef] [PubMed]
[6] 谢云, 高娇, 任茂, 等. 千金苇茎汤合麻杏石甘汤加减联合胸腺法新治疗老年重症肺炎临床观察[J]. 河北中医, 2023, 45(8): 1292-1296+1301.
[7] 马景莲, 郭玉丽, 李春苗, 等. 老年重症肺炎病人预后危险因素分析[J]. 护理研究, 2024, 38(20): 3758-3760.
[8] Zhang, L., Xiao, Y., Zhang, G., Li, H., Zhao, J., Chen, M., et al. (2023) Identification of Priority Pathogens for Aetiological Diagnosis in Adults with Community-Acquired Pneumonia in China: A Multicentre Prospective Study. BMC Infectious Diseases, 23, Article No. 231. [Google Scholar] [CrossRef] [PubMed]
[9] Huang, L., Weng, B., Wang, Y., Wang, M., Mei, Y., Chen, W., et al. (2025) The Effect of Immunosuppression on Outcomes in Elderly Patients with Community-Acquired Pneumonia. Respiratory Research, 26, Article No. 30. [Google Scholar] [CrossRef] [PubMed]
[10] Yatera, K. and Yamasaki, K. (2025) Management of the Diagnosis and Treatment of Pneumonia in an Aging Society. Internal Medicine, 64, 503-517. [Google Scholar] [CrossRef] [PubMed]
[11] 王红燕, 陈高瑛, 齐红松. 生脉散合千金苇茎汤加减治疗痰热壅肺型老年重症肺炎临床研究[J]. 新中医, 2024, 56(3): 11-16.
[12] 邓海燕. 穴位贴敷对老年重症肺炎的护理效果观察[J]. 湖南中医杂志, 2015, 31(3): 120-121+127.
[13] 罗朝湖. 痰热清注射液联合穴位贴敷对老年重症肺炎患者炎症因子的影响[J]. 中国当代医药, 2023, 30(5): 53-56.
[14] 刘冰, 王孟, 俞桂香. “益气宣肺汤”口服联合穴位贴敷辅助治疗老年重症肺炎伴胃肠功能障碍44例临床研究[J]. 江苏中医药, 2024, 56(12): 36-40.
[15] 罗欣悦. 老年重症肺炎患者危险因素分析及风险预测模型构建[D]: [硕士学位论文]. 泸州: 西南医科大学, 2023.
[16] Huang, L., Weng, B., Gu, X., Wang, Y., Wang, M., Weng, J., et al. (2024) Performance of Various Pneumonia Severity Models for Predicting Adverse Outcomes in Elderly Inpatients with Community-Acquired Pneumonia. Clinical Microbiology and Infection, 30, 1426-1432. [Google Scholar] [CrossRef] [PubMed]
[17] Xu, C., Tao, X., Zhu, J., Hou, C., Liu, Y., Fu, L., et al. (2023) Clinical Features and Risk Factors Analysis for Poor Outcomes of Severe Community-Acquired Pneumonia in Children: A Nomogram Prediction Model. Frontiers in Pediatrics, 11, Article 1194186. [Google Scholar] [CrossRef] [PubMed]
[18] Li, Y., Wu, M., Liang, Y., Yang, Y., Guo, W., Deng, Y., et al. (2024) Mycoplasma pneumoniae Infection Outbreak in Guangzhou, China after COVID-19 Pandemic. Virology Journal, 21, Article No. 183. [Google Scholar] [CrossRef] [PubMed]
[19] 陶思冥, 李风森. 中西医结合呼吸内科支气管内镜临床带教与思考[J]. 新疆医学, 2021, 51(5): 512-514.
[20] 孟宪华. 美罗培南治疗老年重症肺炎的有效性和安全性分析[J]. 中外医疗, 2024, 43(7): 80-83.
[21] 王婷婷, 顾永梅, 郑晓燕. 重症监护室后综合征对老年重症肺炎患者症状恢复及功能状态的影响[J]. 中华老年多器官疾病杂志, 2024, 23(12): 943-947.
[22] 张茜茜. 血浆ESM-1联合PCT、IL-6检测在老年重症肺炎的表达及其临床意义[D]: [硕士学位论文]. 承德: 承德医学院, 2023.
[23] 生淑红, 许靖, 付佑辉. 老年重症肺炎患者血清FOXO1、ATG7水平及与短期预后的关系[J]. 国际检验医学杂志, 2024, 45(10): 1218-1222.
[24] Wei, X., Huang, X., Gu, S., Cai, H., Wang, M., Wang, H., et al. (2024) Landscape of Fungal Detection in the Lungs of Patients with Severe Pneumonia in the ICU, a Multicenter Study Based on Clinical Metagenomics. Journal of Infection, 89, Article 106195. [Google Scholar] [CrossRef] [PubMed]
[25] 多克·多丽娜, 范瑞. 呼吸系统感染疾病患者主要病原菌分布及耐药性分析[J]. 新疆医学, 2021, 51(10): 1157-1159+1164.
[26] Jiang, Y., Kang, H., Dou, H., Guo, D., Yuan, Q., Dong, L., et al. (2024) Comparative Genomic Sequencing to Characterize Mycoplasma pneumoniae Genome, Typing, and Drug Resistance. Microbiology Spectrum, 12, e0361523. [Google Scholar] [CrossRef] [PubMed]
[27] 王彤, 季达峰. 老年重症肺炎的危险因素及诊断与治疗进展[J]. 现代医学与健康研究(电子版), 2023, 7(24): 37-40.
[28] 金娴, 潘丽萍. 老年重症肺炎血清炎症因子与预后相关性分析[J]. 贵州医药, 2022, 46(9): 1442-1444.