天然山茶油与莫匹罗星软膏治疗浅表性 包皮龟头炎的疗效比较

Comparison of the Efficacy of Natural Camellia Oil and Mupirocin Ointment in the Treatment of Superficial Balanoposthitis

摘要: 目的：对比天然山茶油与莫匹罗星软膏治疗浅表性包皮龟头炎的临床疗效、安全性及经济性。方法：选取2023年1月~2026年1月我院泌尿男科门诊确诊的90例浅表性包皮龟头炎患者，采用随机数字表法分为观察组(45例)与对照组(45例)。观察组予天然山茶油外涂患处，每日2次；对照组予莫匹罗星软膏外涂患处，每日2次。两组均以1周为1个疗程，观察治疗1周后的临床疗效、症状改善时间及不良反应发生情况，并对比治疗成本。结果：观察组痊愈37例、显效5例、好转2例、无效1例，总有效率94.44%；对照组痊愈35例、显效6例、好转3例、无效1例，总有效率93.33%，两组总有效率比较差异无统计学意义(P > 0.05)。观察组瘙痒缓解时间、皮疹消退时间均短于对照组(P < 0.05)。两组治疗期间均未出现明显不良反应。观察组单疗程治疗成本显著低于对照组(P < 0.05)。结论：天然山茶油治疗浅表性包皮龟头炎疗效与莫匹罗星软膏相当，且具有症状缓解更快、经济成本更低的优势，安全性良好，可作为临床治疗的优选方案之一。

Abstract: Objective: To compare the clinical efficacy, safety and economy of natural camellia oil and mupirocin ointment in the treatment of superficial balanoposthitis. Methods: A total of 90 patients with superficial balanoposthitis diagnosed in the urology and andrology department of our hospital from January 2023 to January 2026 were selected and randomly divided into an observation group (45 cases) and a control group (45 cases) by random number table method. The observation group was treated with natural camellia oil applied to the affected area twice a day; the control group was treated with mupirocin ointment applied to the affected area twice a day. Both groups were treated for one week as one course of treatment. The clinical efficacy, symptom improvement time and adverse reactions after one week of treatment were observed, and the treatment costs were compared. Results: In the observation group, 37 cases were cured, 5 cases were markedly effective, 2 cases were improved, and 1 case was ineffective, with a total effective rate of 94.44%; in the control group, 35 cases were cured, 6 cases were markedly effective, 3 cases were improved, and 1 case was ineffective, with a total effective rate of 93.33%. There was no statistically significant difference in the total effective rate between the two groups (P > 0.05). The time for relief of pruritus and disappearance of rash in the observation group was shorter than that in the control group (P < 0.05). No obvious adverse reactions occurred in both groups during the treatment period. The treatment cost per course in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion: Natural camellia oil has comparable efficacy to mupirocin ointment in the treatment of superficial balanoposthitis, with the advantages of faster symptom relief and lower economic cost, and good safety. It can be considered as one of the preferred treatment options in clinical practice.