中西医治疗糖尿病肾病的研究进展

Research Progress in the Treatment of Diabetic Nephropathy with Integrated Traditional Chinese and Western Medicine

摘要: 糖尿病肾病(Diabetic Kidney Disease, DKD)是终末期肾病的主要原因之一，是糖尿病最严重且最常见的微血管病变之一。目前，西医对DKD常通过调节血糖、血脂、降压来治疗，一定程度上可控制疾病的进展，但用药存有不良反应和用药局限性。中医药通过整体调节和辨证论治，在改善症状、减少西药不良反应方面显示出独特优势。此综述主要结合中医病因病机、中医治疗方法、西医诊断、流行病学、危险因素、西医治疗方法以及中西医联合治疗展开论述。旨在总结前人经验，阐述DKD的中西医认识及诊疗方法，为临床提供参考。

Abstract: Diabetic Kidney Disease (DKD) is one of the leading causes of End-Stage Renal Disease (ESRD) and ranks among the most severe and prevalent microvascular complications of diabetes mellitus. Currently, Western medicine primarily intervenes in DKD via glycemic control, lipid regulation and antihypertensive therapy, which can slow disease progression to a certain degree. Nevertheless, Western medications are associated with adverse reactions and inherent limitations in clinical application. Traditional Chinese Medicine (TCM) features holistic regulation and treatment based on syndrome differentiation, and presents unique superiorities in relieving clinical symptoms and mitigating adverse reactions of Western drugs. This review mainly elaborates on DKD from the perspectives of TCM etiology and pathogenesis, TCM therapeutic regimens, Western medical diagnosis, epidemiology, risk factors, Western medical interventions, as well as integrated Chinese and Western medicine therapy. It aims to summarize previous research findings, expound the cognition, diagnosis and treatment approaches of DKD in both TCM and Western medicine, and provide references for clinical practice.