Ag基量子点生物应用研究进展
Research Progress on the Biological Applications of Ag-Based Quantum Dots
摘要: Ag基量子点(Ag-based Quantum Dots)作为一类新型无镉量子点材料，凭借其可调的光学性能、良好的生物相容性及优异的荧光特性，在生物医学领域展现出巨大的应用潜力。如何实现Ag基量子点的可控合成、高效功能化修饰及安全高效的生物应用，是当前该领域的核心研究重点。本文系统综述了Ag基量子点的典型合成方法，总结了其生物功能化修饰策略与表面改性途径，重点阐述了其在生物传感检测、活体生物成像以及肿瘤靶向诊疗等方面的研究进展，并对Ag基量子点在生物医学应用中面临的挑战与发展前景进行了展望，以期为Ag基量子点的进一步生物应用与临床转化提供理论参考与研究思路。
Abstract: Ag-based quantum dots, as a new type of cadmium-free quantum dot material, exhibit great potential in the biomedical field due to their tunable optical properties, good biocompatibility, and excellent fluorescence characteristics. The key research focus in this field currently is how to achieve controlled synthesis of silver-based quantum dots, efficient functional modification, and safe and effective biological applications. This article systematically reviews typical synthesis methods of silver-based quantum dots, summarizes their biological functionalization strategies and surface modification approaches, and highlights research progress in biosensing detection, in vivo bioimaging, and tumor-targeted diagnosis and treatment. Furthermore, it discusses the challenges and development prospects of silver-based quantum dots in biomedical applications, aiming to provide theoretical references and research ideas for their further biological applications and clinical translation.
文章引用：庞今祎. Ag基量子点生物应用研究进展[J]. 应用物理, 2026, 16(5): 447-455. https://doi.org/10.12677/app.2026.165041

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