皮肤抗氧化策略的流程、评估与新趋势

Process, Evaluation, and New Trends of Skin Antioxidant Strategies

摘要: 为系统梳理皮肤抗氧化领域的当前进展与挑战，本文综述了以氧化应激为核心的皮肤老化机制及多层次评估策略。文章通过聚焦氧化应激这一皮肤老化的核心枢纽，详细地梳理并整合了从基础功效研究到探索分子机制与临床验证的多层次、递进式评估策略框架，着重探讨了新兴科技如何驱动该领域向更精准、客观、便利的方向发展，例如分析了组学技术与人工智能等新方法在揭示作用机制与提升评估效能方面的最新应用，并最终展望了跨学科融合与个性化干预的未来趋势，以期为相关研究者与从业者提供全面的参考与指引。相较于既往研究，本综述提出并强调了跨学科整合与个性化策略的未来趋势，旨在为研究者提供一套系统的评估框架与前沿视角，推动皮肤抗氧化研究向更精准、规范化的方向发展。

Abstract: To systematically synthesize the current advances and challenges in the field of skin antioxidant research, this review summarizes the mechanisms of skin aging centered on oxidative stress and multi-level evaluation strategies. By focusing on oxidative stress as the core hub of skin aging, this article comprehensively organizes and integrates a multi-level, progressive evaluation strategy framework spanning basic efficacy studies, molecular mechanism exploration, and clinical validation. It specifically investigates how emerging technologies drive the field toward greater precision, objectivity, and accessibility—for instance, analyzing the latest applications of omics technologies and artificial intelligence in elucidating mechanisms of action and enhancing evaluation efficacy. Finally, it anticipates future trends in interdisciplinary integration and personalized intervention, with the aim of providing comprehensive references and guidance for relevant researchers and practitioners. In contrast to prior studies, this review proposes and emphasizes the future trends of interdisciplinary integration and personalized strategies, seeking to equip researchers with a systematic evaluation framework and cutting-edge perspectives, thereby facilitating the advancement of skin antioxidant research toward greater precision and standardization.