积极心理干预对脑胶质瘤术后化疗患者负性情绪的影响

Effects of Positive Psychological Intervention on Negative Emotions in Patients with Glioma after Postoperative Chemotherapy

摘要: 目的：探讨积极心理干预应用于脑胶质瘤术后化疗患者，对其焦虑、抑郁负性情绪的改善效果，通过焦虑自评量表(SAS)、抑郁自评量表(SDS)量化评估干预价值，为临床神经肿瘤护理提供优化方案。方法：选取我院神经外科2024年1月~2025年1月收治的86例脑胶质瘤术后化疗患者，采用随机数字表法分为对照组与观察组，各43例。对照组实施脑胶质瘤术后化疗常规护理，观察组在常规护理基础上联合系统化积极心理干预，干预周期为整个化疗疗程(4个周期，每周期21天)。分别于干预前、化疗2个周期后、化疗结束后，采用SAS、SDS量表评估两组患者焦虑、抑郁情绪变化，同时对比两组患者化疗依从性与护理满意度。结果：干预前，两组患者SAS、SDS评分比较，差异无统计学意义(P > 0.05)；干预后各时间节点，两组评分均较干预前有所下降，且观察组SAS、SDS评分明显低于对照组，差异具有统计学意义(P < 0.05)；观察组化疗总依从率及护理总满意度均高于对照组，差异有统计学意义(P < 0.05)。结论：积极心理干预可有效缓解脑胶质瘤术后化疗患者的焦虑、抑郁负性情绪，降低心理应激水平，提升患者治疗依从性与护理满意度，助力患者顺利完成化疗，改善整体预后，值得临床推广。

Abstract: Objective: The objective of this paper is to investigate the effect of positive psychological intervention on alleviating anxiety and depression in patients with glioma undergoing postoperative chemotherapy, quantitatively evaluate the intervention value using the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS), and provide an optimized scheme for clinical neuro-oncology nursing. Methods: A total of 86 patients with glioma receiving postoperative chemotherapy in the Department of Neurosurgery of our hospital from January 2024 to January 2025 were enrolled and randomly divided into a control group and an observation group, with 43 cases in each group. The control group received routine nursing care during postoperative chemotherapy for glioma, while the observation group was given additional systematic positive psychological intervention on the basis of routine nursing. The intervention lasted for the entire chemotherapy course (4 cycles, 21 days per cycle). The SAS and SDS were used to assess anxiety and depression before intervention, after 2 cycles of chemotherapy, and at the end of chemotherapy. Chemotherapy compliance and nursing satisfaction were also compared between the two groups. Results: There were no significant differences in SAS and SDS scores between the two groups before intervention (P > 0.05). At each time point after intervention, the scores in both groups were lower than those before intervention, and the SAS and SDS scores in the observation group were significantly lower than those in the control group, showing statistically meaningful differences (P < 0.05). The total chemotherapy compliance rate and total nursing satisfaction rate in the observation group were higher than those in the control group, with statistically significant differences (P < 0.05). Conclusion: Positive psychological intervention can effectively relieve anxiety and depression in patients with glioma undergoing postoperative chemotherapy, reduce psychological stress, improve treatment compliance and nursing satisfaction, help patients complete chemotherapy smoothly, and improve the overall prognosis. It is worthy of clinical promotion.