人工智能在结缔组织病相关间质性肺病进展型肺纤维化中的应用及研究进展
Advances and Research Progress in the Application of Artificial Intelligence for Progressive Pulmonary Fibrosis in Connective Tissue Disease-Associated Interstitial Lung Disease
DOI: 10.12677/acm.2026.1652018, PDF,   
作者: 王佳琳：江汉大学医学部，湖北 武汉；孙 珊：华中科技大学同济医学院附属武汉中心医院全科医学科，湖北 武汉；林桂丽：汕头大学医学院第一附属医院全科医学分院，广东 汕头；刘晓帆*：华中科技大学同济医学院附属武汉中心医院呼吸与危重症医学科，湖北 武汉
关键词: 结缔组织病相关间质性肺病；进展型肺纤维化；人工智能；Connective Tissue Disease-Associated Interstitial Lung Disease； Progressive Pulmonary Fibrosis； Artificial Intelligence
摘要: 结缔组织病相关间质性肺病(CTD-ILD)是结缔组织病(CTD)引发的肺部并发症之一。其中一部分患者会发展为进展型肺纤维化(PPF)表型，在确诊后患者肺功能不可逆的肺损伤、死亡率增加。近年来，基于人工智能在影像学上取得显著的进展，本文系统地阐述了AI在CTD-ILD进展型肺纤维化中的应用现状、关键技术、临床转化挑战及未来发展方向。
Abstract: Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) is one of the pulmonary complications caused by connective tissue diseases (CTD). A portion of these patients will develop the progressive pulmonary fibrosis (PPF) phenotype. After diagnosis, patients suffer irreversible lung damage and an increased mortality rate. In recent years, with significant progress in artificial intelligence in imaging, this article systematically elaborates on the current application status, key technologies, clinical transformation challenges, and future development directions of AI in CTD-ILD progressive pulmonary fibrosis.
文章引用：王佳琳, 孙珊, 林桂丽, 刘晓帆. 人工智能在结缔组织病相关间质性肺病进展型肺纤维化中的应用及研究进展[J]. 临床医学进展, 2026, 16(5): 2107-2115. https://doi.org/10.12677/acm.2026.1652018

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