羽扇豆醇的药理作用及其相关分子机制的研究

Research on the Pharmacological Effects and Related Molecular Mechanisms of Lupeol

摘要: 羽扇豆醇是一种可从冰花种皮、蒲公英、白桦树皮等多种天然植物中提取获得的天然活性成分。该物质属于天然三萜类化合物，因其来源丰富、安全性良好，已成为天然药物研发领域的研究热点。研究表明，羽扇豆醇具备抗肿瘤、抗炎、缓解氧化应激损伤及改善2型糖尿病等多种药理活性。本文对近年来羽扇豆醇的药理作用及其分子机制的相关研究进展进行综述，为羽扇豆醇的开发和临床研究提供理论依据。

Abstract: Lupeol is a natural active ingredient that can be extracted from various natural plants, including the seed coat of Mesembryanthemum crystallinum, dandelion, and birch bark. As a natural triterpenoid, it has become a research hotspot in the field of natural drug development due to its wide sources and high safety. Studies have shown that lupeol possesses various pharmacological activities, such as anti-tumor, anti-inflammatory, alleviating oxidative stress injury, and ameliorating type 2 diabetes mellitus. This article reviews the recent research progress on the pharmacological effects and molecular mechanisms of lupeol, so as to provide a theoretical basis for its development and clinical research.