桃红四物汤合五苓散治疗糖尿病足溃疡的运用价值和研究进展

Application Value and Research Progress of Taohong Siwu Decoction Combined with Wuling Powder in Treating Diabetic Foot Ulcer

摘要: 糖尿病足溃疡是临床常见慢性病症，血糖水平过高、周围神经出现病变、下肢血液流动不畅以及伤口感染等多种因素，都会影响它的形成与发展。目前不少研究都在关注这类溃疡不同致病因素的具体治疗手段，并且已经取得了不错的临床效果。桃红四物汤与五苓散搭配使用的复合方剂，是传统中用于养血通脉、通阳利水的经典方剂，相关药理学研究发现它能起到抗炎、镇痛、缓解痉挛、防止血液凝固、调节免疫功能、让末梢血液循环更顺畅、提高神经传导速度以及抑制细菌等多种作用——这些作用刚好和糖尿病足溃疡的病理机制相契合。关于桃红四物汤合五苓散在糖尿病足溃疡治疗里能发挥怎样的实际效果、还有哪些应用潜力，还需要进一步开展研究和讨论。

Abstract: Diabetic foot ulcer is a common chronic clinical condition influenced by multiple factors including elevated blood glucose levels, peripheral neuropathy, impaired lower limb blood circulation, and wound infections, all of which contribute to its formation and progression. Numerous studies have focused on specific therapeutic approaches targeting these diverse pathogenic factors, with promising clinical outcomes already achieved. The compound formulation combining Taohong Siwu Decoction combined with Wuling Powder is a classic traditional prescription used for nourishing blood, promoting meridian flow, activating yang, and facilitating diuresis. Pharmacological studies have demonstrated its multifaceted effects, including anti-inflammatory, analgesic, antispasmodic, anticoagulant, immunomodulatory, improved peripheral microcirculation, enhanced nerve conduction velocity, and antibacterial properties—effects that align precisely with the pathological mechanisms of diabetic foot ulcer. Further research and discussion are warranted to elucidate the actual therapeutic efficacy and untapped potential of Taohong Siwu Decoction combined with Wuling Powder in the treatment of diabetic foot ulcer.