薯蓣皂苷与炎症防治
Dioscin and the Prevention and Treatment of Inflammation
DOI: 10.12677/pi.2026.153027, PDF,    国家自然科学基金支持
作者: 邓嘉磊, 邓汝彬, 赖 敏, 廖海荣*, 杨树龙*：抚州市慢性病研究技术创新中心，江西 抚州；南昌大学抚州医学院生理学教研室，江西 抚州；南昌大学抚州医学院慢性病研究重点实验室，江西 抚州
关键词: 薯蓣皂苷；炎症；NF-κB；Dioscin； Inflammation； NF-κB
摘要: 薯蓣皂苷(Dioscin)作为一种甾体皂苷类天然产物，具有显著的抗炎作用。文章通过整理相关文献，从抑制炎症介质产生、抗氧化应激、抑制炎症反应的信号通路和调节免疫细胞功能、降低促炎细胞因子的释放方面，综述薯蓣皂苷的抗炎作用机制，以期为天然产物在炎症相关疾病新型治疗中的开发提供重要的理论依据。
Abstract: Dioscin, a natural steroidal saponin, exhibits significant anti-inflammatory effects. This paper reviews the anti-inflammatory mechanisms of dioscin by organizing relevant literature, focusing on the inhibition of inflammatory mediator production, antioxidative stress, suppression of inflammatory signaling pathways, regulation of immune cell function, and reduction of pro-inflammatory cytokine release. It aims to provide an important theoretical basis for the development of novel therapies using natural products in inflammation-related diseases.
文章引用：邓嘉磊, 邓汝彬, 赖敏, 廖海荣, 杨树龙. 薯蓣皂苷与炎症防治[J]. 药物资讯, 2026, 15(3): 243-250. https://doi.org/10.12677/pi.2026.153027

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