康普瑞汀的药理作用及分子机制研究进展
Research Progress on the Pharmacological Effects and Molecular Mechanism of Combretastatin A4
DOI: 10.12677/acm.2026.1652158, PDF,    科研立项经费支持
作者: 赵文慧, 李红叶, 黄曦醇, 权 泉, 李君豪, 宁 钊, 金成浩*：黑龙江八一农垦大学生命科学技术学院，黑龙江 大庆
关键词: 康普瑞汀；抗肿瘤；抗炎；抗真菌；免疫调节；Combretastatin A4； Anti-Tumor； Anti-Inflammatory； Antifungal； Immune Regulation
摘要: 康普瑞汀源自南非风车子的树皮组织，属于天然二苯乙烯类酚类活性成分。大量药理研究表明，该天然产物在抗肿瘤、抗炎、抗真菌以及调控机体免疫功能等方面均展现出突出的生物活性。本文汇总梳理近年来康普瑞汀药理功效与分子作用机制的相关研究成果，全面阐述其作用特点与调控规律，为该化合物的深度基础研究、药用价值挖掘及候选药物研发奠定理论基础。
Abstract: Combretastatin A4 is derived from the bark tissue of the South African windmill tree and belongs to the natural stilbene phenolic active component. A large number of pharmacological studies have shown that this natural product has outstanding biological activities in anti-tumor, anti-inflammatory, anti-fungal and regulation of the immune function of the body. This article summarizes and sorts out the relevant research results of the pharmacological effects and molecular action mechanisms of Combretastatin A4 in recent years, comprehensively expounds its action characteristics and regulation rules, and lays a theoretical foundation for the in-depth basic research, medicinal value exploration and candidate drug development of this compound.
文章引用：赵文慧, 李红叶, 黄曦醇, 权泉, 李君豪, 宁钊, 金成浩. 康普瑞汀的药理作用及分子机制研究进展[J]. 临床医学进展, 2026, 16(5): 3369-3374. https://doi.org/10.12677/acm.2026.1652158

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