呼吸道合胞病毒感染继发哮喘的研究进展
Research Progress on Asthma Secondary to Respiratory Syncytial Virus
DOI: 10.12677/acm.2026.1662219, PDF,   
作者: 王向楠：承德医学院研究生学院，河北 承德；黄秋芳*：保定市第一中心医院普儿科，河北 保定
关键词: 呼吸道合胞病毒；哮喘；发病机制；儿童；脂质代谢；防治策略；Respiratory Syncytial Virus； Asthma； Pathogenesis； Children； Lipid Metabolism； Prevention Strategies
摘要: 系统综述呼吸道合胞病毒(RSV)感染与儿童哮喘发生发展的关联，阐述RSV感染通过气道上皮功能障碍、免疫应答异常、脂质代谢双向调控及易感基因调控等机制诱发哮喘的分子路径，分析病毒基因型、宿主因素及环境因素的协同调控作用，并总结当前防御策略，为RSV感染相关哮喘的早期识别及临床干预提供理论支撑。
Abstract: This review systematically summarizes the association between respiratory syncytial virus (RSV) infection and the development and progression of childhood asthma. It elaborates on the molecular pathways through which RSV infection induces asthma, including airway epithelial dysfunction, immune response abnormalities, bidirectional regulation of lipid metabolism, and susceptibility gene regulation. It also analyzes the synergistic regulatory roles of viral genotypes, host factors, and environmental exposures, and summarizes current prevention and treatment strategies, thereby providing theoretical support for the early recognition and clinical intervention of RSV-associated asthma.
文章引用：王向楠, 黄秋芳. 呼吸道合胞病毒感染继发哮喘的研究进展[J]. 临床医学进展, 2026, 16(6): 281-287. https://doi.org/10.12677/acm.2026.1662219

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