基于“癖囊”理论探讨多囊卵巢综合征 所致不孕

Exploring Infertility Caused by Polycystic Ovary Syndrome Based on the “Pinang” Theory

摘要: 多囊卵巢综合征(Polycystic ovary syndrome, PCOS)是一种常见的代谢异常和生殖障碍性疾病，是导致育龄期女性不孕的主要原因。本研究团队发现，中医“癖囊”理论能准确阐述PCOS不孕的病理状态，认为PCOS所致不孕的关键病机乃脾肾阳虚为本、痰浊内蕴为标。PCOS患者多先天肾气不足，肾阳虚衰，脾失运化，导致脾肾阳虚，津液代谢失常，聚为痰浊，痰浊壅阻卵巢，蒙蔽卵子，形成“癖囊”，进而阻碍卵泡发育、排出及胚胎着床，最终导致不孕。基于此理论，本团队以温肾健脾、化痰消癖为基本治法，自拟补肾化痰方，并结合月经周期分期论治，为中医药诊治PCOS不孕提供理论依据与临床参考。

Abstract: Polycystic ovary syndrome (PCOS) is a common metabolic and reproductive disorder and a leading cause of infertility in women of reproductive age. Our research team has found that the traditional Chinese medicine theory of “Pinang” can accurately explain the pathological condition of infertility caused by PCOS. It is believed that the key pathogenesis of infertility caused by PCOS lies in the deficiency of spleen and kidney yang as the root, and the internal accumulation of phlegm-dampness as the manifestation. PCOS patients often have congenital insufficiency of kidney qi, kidney yang deficiency, and impaired spleen transportation, leading to spleen and kidney yang deficiency, abnormal fluid metabolism, accumulation of phlegm-dampness, which obstructs the ovaries and conceals the oocytes, forming “Pinang”, thereby hindering follicle development, ovulation, and embryo implantation, ultimately causing infertility. Based on this theory, our team uses kidney-warming and spleen-strengthening, phlegm-resolving, and Pinang-eliminating as the basic treatment method, and we have developed our own prescription to tonify the kidney and resolve phlegm, combined with menstrual cycle stage-based treatment, providing a theoretical basis and clinical reference for the TCM diagnosis and treatment of PCOS-related infertility.