下肢深静脉血栓进展为肺栓塞的危险因素：一项综合评述
Risk Factors for the Progression from Deep Vein Thrombosis to Pulmonary Embolism: A Comprehensive Review
DOI: 10.12677/jcpm.2026.53186, PDF,    科研立项经费支持
作者: 牟小民：济宁医学院临床医学院，山东 济宁；靳 松, 孙自强*：济宁医学院附属医院血管外科，山东 济宁
关键词: 下肢深静脉血栓；肌间静脉血栓形成；肺栓塞；预测；Lower Extremity Deep Vein Thrombosis； Muscle Calf Venous Thrombosis； Pulmonary Embolism； Predict
摘要: 下肢深静脉血栓(DVT)的发生部位不同，其继发肺栓塞(PE)的风险、诊断策略、严重程度及临床管理仍存在诸多争议，这直接导致了治疗决策的不一致。目前，近端DVT的治疗已形成共识，但对于更为常见的小腿肌间静脉血栓(MCVT)，相关研究尚不全面，也缺乏统一、明确的临床管理指南。此外，现有多数研究在探讨DVT时未能充分控制或分析混杂因素，致使具有高证据价值的研究相对有限。为此，本综述旨在系统整合与比较不同部位下肢DVT患者发生PE的频率及严重程度，深入探讨血栓部位与PE发生之间的潜在关联，以期为临床医师和研究者提供一个更全面、深入的视角，从而更好地理解下肢DVT及其并发症，优化临床实践。
Abstract: The risk, diagnostic approach, severity, and clinical management of pulmonary embolism (PE) secondary to lower extremity deep vein thrombosis (DVT) remain controversial depending on the location of the thrombosis, leading directly to inconsistencies in treatment decisions. Currently, the management of proximal DVT is well-established; however, research on the more common muscular calf vein thrombosis (MCVT) remains insufficient, and a unified, clear clinical management guideline is lacking. Furthermore, most existing studies on DVT have failed to adequately control or analyze confounding factors, resulting in a relative scarcity of high-quality, valuable evidence. Therefore, this review aims to systematically integrate and compare the frequency and severity of PE in patients with lower extremity DVT at different sites, explore the potential relationship between thrombus location and the occurrence of PE, and provide clinicians and researchers with a more comprehensive and in-depth perspective to better understand lower extremity DVT and its complications, thereby optimizing clinical practice.
文章引用：牟小民, 靳松, 孙自强. 下肢深静脉血栓进展为肺栓塞的危险因素：一项综合评述[J]. 临床个性化医学, 2026, 5(3): 86-92. https://doi.org/10.12677/jcpm.2026.53186

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