良性前列腺增生患者经尿道激光剜除术后膀胱过度活动症发生的研究进展
Research Progress on the Occurrence of Overactive Bladder after Laser Enucleation of the Prostate in Patients with Benign Prostatic Hyperplasia
DOI: 10.12677/acm.2026.1662282, PDF,    科研立项经费支持
作者: 李振华：山西医科大学第一临床医学院，山西 太原；马志方*：山西医科大学第一临床医学院，山西 太原；山西医科大学第一医院泌尿外科，山西 太原
关键词: 良性前列腺增生；前列腺激光剜除术；膀胱过度活动症；米拉贝隆；Benign Prostatic Hyperplasia； Laser Enucleation of the Prostate； Overactive Bladder； Mirabegron
摘要: 良性前列腺增生(Benign Prostatic Hyperplasia, BPH)是一种好发于中老年男性的良性疾病，其主要症状为排尿困难、尿频、尿急、尿不尽等。现有研究尚未明确BPH的发病原因，可能是年龄、生活习惯、性激素以及炎症等多种因素相互作用共同导致的结果。绝大多数BPH患者可以通过长期药物治疗来改善症状，而对于保守治疗无效或合并其他并发症的患者，选择合适的手术方式，缓解患者的下尿路症状，减轻其疾病负担，提升其生活质量。经尿道激光剜除术是目前大小体积前列腺增生患者均适用的手术方法，但术后膀胱过度活动症(Overactive Bladder, OAB)尤其是急迫性尿失禁的发生严重影响了手术疗效，为患者带来了诸多困扰。本文就BPH患者经尿道激光剜除术后OAB发生的影响因素以及目前的治疗策略等相关进展作一综述。
Abstract: Benign Prostatic Hyperplasia (BPH) is a common benign disease that frequently affects middle-aged and elderly men. Its main symptoms include difficulty in urination, frequent urination, urgency, incomplete urination, etc. Current research has not yet clearly identified the cause of BPH. It may be the result of the interaction of various factors such as age, lifestyle, sex hormones, and inflammation. The majority of BPH patients can improve their symptoms through long-term drug treatment. For those who do not respond to conservative treatment or have other complications, choosing an appropriate surgical method to relieve the lower urinary tract symptoms, reduce the disease burden, and improve their quality of life is necessary. Transurethral laser enucleation is currently a surgical method applicable to patients with both small and large volume prostate hyperplasia. However, the occurrence of overactive bladder (OAB), especially urge urinary incontinence after the surgery, has seriously affected the surgical efficacy and brought many troubles to the patients. This article reviews the influencing factors of OAB occurrence after transurethral laser enucleation in BPH patients and the current treatment strategies and related progress.
文章引用：李振华, 马志方. 良性前列腺增生患者经尿道激光剜除术后膀胱过度活动症发生的研究进展[J]. 临床医学进展, 2026, 16(6): 820-827. https://doi.org/10.12677/acm.2026.1662282

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