卒中后基底节失语症的致病机制研究进展
Research Progress on the Pathogenic Mechanisms of Post-Stroke Basal Ganglia Aphasia
DOI: 10.12677/acm.2026.1662288, PDF,   
作者: 梁曦月：黑龙江中医药大学研究生院，黑龙江 哈尔滨；李晓宁*：黑龙江中医药大学附属第二医院针灸四科，黑龙江 哈尔滨
关键词: 卒中后基底节失语症；断联假说；白质纤维束；皮质低灌注；综述；Post-Stroke Basal Ganglia Aphasia； Disconnection Hypothesis； White Matter Tracts； Cortical Hypoperfusion； Review
摘要: 卒中后基底节失语症(PSBGA)是皮质下卒中后常见的语言障碍，以命名能力受损为核心特征，伴随言语流畅度、发音和韵律困难，复述能力相对保留。目前其致病机制尚未完全阐明。近年来，扩散谱成像(DSI)等先进神经影像技术的发展，使得精细解析基底节区域复杂白质纤维束成为可能。本文对近年来卒中后基底节失语症致病机制的研究进展作一综述，旨在为卒中后基底节失语症发病机制的阐明以及患者语言功能恢复方案的制定提供新思路。
Abstract: Post-stroke basal ganglia aphasia (PSBGA) is a common language disorder following subcortical stroke, characterized by impaired naming ability as the core feature, accompanied by difficulties in speech fluency, articulation, and prosody, with relatively preserved repetition ability. The pathogenic mechanisms of PSBGA remain not fully elucidated. In recent years, advances in advanced neuroimaging techniques such as diffusion spectrum imaging (DSI) have enabled detailed analysis of the complex white matter tracts in the basal ganglia region. This article reviews the research progress on the pathogenic mechanisms of post-stroke basal ganglia aphasia in recent years, aiming to provide new insights for elucidating the pathogenesis of PSBGA and developing strategies for the recovery of language function in affected patients.
文章引用：梁曦月, 李晓宁. 卒中后基底节失语症的致病机制研究进展[J]. 临床医学进展, 2026, 16(6): 869-874. https://doi.org/10.12677/acm.2026.1662288

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