赵珂主任从疏肝补肾法辨治高泌乳素血症所致月经疾病经验浅析
A Brief Analysis of Director Zhao Ke’s Experience in Treating Menstrual Disorders Caused by Hyperprolactinemia through the Liver-Soothing and Kidney-Tonifying Method
DOI: 10.12677/tcm.2026.156326, PDF,   
作者: 崔文澜*:天津市中医药研究院附属医院临床试验机构办公室,天津;霍欣妍:天津中医药大学研究生院,天津;赵 珂#:天津市中医药研究院附属医院妇科,天津
关键词: 疏肝补肾法高泌乳素血症月经疾病临床病案理论探讨Liver-Soothing and Kidney-Tonifying Method Hyperprolactinemia Menstrual Disorders Clinical Case Record Theoretical Discussion
摘要: 高泌乳素血症(HPRL)是指由于各种原因导致患者血清中泌乳素(PRL)水平异常升高的一种临床疾病。在女性患者中,多数同时伴有月经紊乱甚至闭经、泌乳和不孕等表现,严重影响生活质量。西医治疗本病,其方法主要包括以多巴胺受体激动剂为代表的药物治疗、手术治疗及放射治疗等,因其均存在较大的不良反应或疗效不确定,故而部分患者难以接受。中医论治该病,可将其归为“闭经”“月经先后不定期”“月经过少”等。赵珂主任临证每从肝、肾两脏入手,因于乙癸同源,治以疏肝补肾,多有效验。本文从此法立论,浅析赵珂主任治疗此病经验,并附验案1则,以期有益于同道。
Abstract: Hyperprolactinemia (HPRL) refers to a clinical condition characterized by abnormally elevated levels of prolactin (PRL) in the serum of patients due to various causes. Among female patients, most also suffer from menstrual disorders, even amenorrhea, galactorrhea and infertility, which seriously affect their quality of life. In western medicine, the treatment methods for this disease mainly include pharmacological therapy represented by dopamine receptor agonists, surgical therapy, and radiotherapy. In traditional Chinese medicine, this disease can be classified as “amenorrhea”, “irregular menstruation”, “oligomenorrhea”, etc. Director Zhao Ke always starts with the liver and kidneys in clinical practice, considering that the liver and kidneys share a common origin, she treats patients by liver-soothing and kidney-tonifying method, which often proves effective. This article is based on this method, providing a brief analysis of director Zhao Ke’s experience in treating this disease, and appending a verified case, in the hope of benefiting fellow practitioners.
文章引用:崔文澜, 霍欣妍, 赵珂. 赵珂主任从疏肝补肾法辨治高泌乳素血症所致月经疾病经验浅析[J]. 中医学, 2026, 15(6): 159-163. https://doi.org/10.12677/tcm.2026.156326

参考文献

[1] 梅全喜. 现代中药药理临床应用手册[M]. 北京: 中国中医药出版社, 2016: 359-360, 794-796.
[2] 金泽祥, 王雄. 白芍提取物通过多巴胺D2受体治疗大鼠高泌乳素血症[J]. 中成药, 2016, 38(4): 741-745.
[3] 黄念. 精神类药物导致女性高催乳素血症中医证候和相关因素分析[D]: [硕士学位论文]. 北京: 北京中医药大学, 2020.
[4] 周夏, 王嘉梅. 王嘉梅治疗高泌乳素血症经验总结[J]. 光明中医, 2020, 35(12): 1811-1813.
[5] 顿彩虹, 白爱红, 谢文燕, 等. 菟丝子总黄酮对大鼠卵巢储备功能减退的改善作用[J]. 广州中医药大学学报, 2022, 39(2): 388-394.
[6] 孙向明, 宋辉, 赵丽珠, 等. 菟丝子拟雌激素作用体内直接作用物质的发现[J]. 药学学报, 2021, 56(7): 1826-1813.
[7] 徐鸿燕, 许昕. 许昕平冲降逆法论治女性高泌乳素血症[J]. 国际中医中药杂志, 2020, 42(10): 1014-1017.
[8] 张雅冬, 许昕. 许昕教授治疗妇科疾病经验[J]. 天津中医药, 2019, 36(12): 1196-1199.
[9] 刘雪娥, 周月红, 荣三群, 等. 逍遥散加减治疗高泌乳素血症有效性和安全性的Meta分析[J]. 中国中医药图书情报杂志, 2023, 47(3): 110-115.
[10] 廖丽, 黄洁, 奉家豪, 等. 基于“乳为肝窍”理论探讨柴胡疏肝散对高泌乳素血症大鼠乳腺组织及性激素的影响[J]. 现代中西医结合杂志, 2020, 29(20): 2179-2183.
[11] 马堃, 刘晓倩, 李佳妮. 补肾促卵冲剂治疗高泌乳素导致排卵障碍性不孕调节性激素相关机制的研究[J]. 中国中药杂志, 2024, 49(8): 1996-2005.
[12] 沈皓, 蔡德培, 陈伯英. 补肾中药对下丘脑-垂体促性腺机能的影响[J]. 中西医结合学报, 2004, 2(1): 53-57.