生殖支原体感染与女性不孕的关系及对 白带结果的影响

Association of Mycoplasma genitalium Infection with Female Infertility and Its Impact on Vaginal Discharge Parameters

摘要: 目的：探讨生殖支原体(Mg)感染与女性不孕的关系及对白带结果的影响。方法：选取2023年7月~2025年4月在内江市妇幼保健院接受检查的150例女性不孕症患者作为观察组，另选取同期于本院接受体检的150例女性作为对照组。采用逆转录–聚合酶链反应(RT-PCR)检测生殖道Mg感染情况，比较两组的Mg阳性检出率，分析生殖道Mg感染与女性不孕的关系及对白带的影响。结果：相比于对照组，观察组的Mg阳性率更高，11.33% vs. 3.33% (P < 0.05)。观察组和对照组的白带清洁度、白细胞、上皮细胞、霉菌、滴虫、线索细胞检出结果对比，差异无统计学意义(P > 0.05)。结论：女性不孕症患者的Mg感染率较高，Mg感染可能与女性不孕的发生有关，而对白带结果的影响仍有待进一步验证。

Abstract: Objective: To explore the relationship between Mycoplasma genitalium (Mg) infection and female infertility, as well as its influence on vaginal discharge test results. Methods: A total of 150 female infertility patients who underwent examination at Neijiang Maternal and Child Health Hospital from July 2023 to April 2025 were enrolled as the observation group, and another 150 healthy females who received physical examination in the hospital during the same period were selected as the control group. Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect genital Mg infection. The positive detection rate of Mg was compared between the two groups, and the correlation of genital Mg infection with female infertility and its impact on vaginal discharge indicators were analyzed. Results: The positive rate of genital Mg in the observation group was significantly higher than that in the control group, accounting for 11.33% versus 3.33% (P < 0.05). There were no statistically significant differences in the vaginal discharge cleanliness grade, and the detection results of leukocytes, epithelial cells, fungi, trichomonas and clue cells between the two groups (P > 0.05). Conclusion: The genital Mg infection rate is elevated in female infertility patients. Genital Mg infection may be associated with the occurrence of female infertility, while its effect on vaginal discharge test results remains to be further verified.