三白汤及其各单味药在皮肤美白方面的 研究进展
Research Progress on San-Bai Decoction and Its Individual Herbs in Skin Whitening
摘要: 近年来，三白汤作为中医美容经典方剂，凭借其多成分、多靶点的美白功效，在皮肤美白研究领域备受关注，成为开发安全、高效的中药来源美白产品的重要研究对象。本文通过整理国内外相关文献，综述了三白汤美白作用的现代研究进展，阐述了其全方及各单味药通过抑制酪氨酸酶、抗氧化、抗炎等多途径发挥美白作用的机制。最后，论述了三白汤外用制剂开发可能存在的挑战，总结并指出现阶段研究仍然存在的不足，并对该方在皮肤美白领域的未来研究方向进行了展望，以期为三白汤的深度开发与成果转化提供参考。
Abstract: In recent years, San-Bai decoction, as a classic formula in traditional Chinese medicine cosmetology, has garnered significant attention in the field of skin whitening research due to its multi-component, multi-target whitening effects, establishing itself as an important subject for the development of safe and efficient whitening products derived from traditional Chinese medicine. This article reviews the progress of modern research on the whitening effects of San-Bai decoction by synthesizing relevant domestic and international literature, elucidating the mechanisms through which the whole formula and its individual herbs exert whitening effects via multiple pathways, including inhibiting tyrosinase, providing antioxidant effects, and reducing inflammation. Finally, Finally, it discusses the potential challenges in the development of topical formulations of San-Bai Decoction, summarizes the current limitations in research, and offers perspectives on future research directions for this formula in the field of skin whitening, aiming to provide a reference for the in-depth development and translational application of San-Bai Decoction.
文章引用：胡佳茜, 张兴江, 吴建新, 黄庆. 三白汤及其各单味药在皮肤美白方面的 研究进展[J]. 临床医学进展, 2026, 16(6): 1066-1075. https://doi.org/10.12677/acm.2026.1662312

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