膳食模式与胆石症关联的研究进展
Research Progress on the Association between Dietary Patterns and Gallstone Disease
DOI: 10.12677/acm.2026.1662335, PDF,   
作者: 郎哲涛, 王二辉*：绍兴大学医学院，浙江 绍兴
关键词: 胆结石；膳食模式；作用机制；综述；Gallstones； Dietary Patterns； Mechanisms of Action； Review
摘要: 胆石症是一种常见的消化系统慢性疾病，其发生发展与遗传及多种环境因素密切相关。大量流行病学研究表明，膳食因素在胆结石形成过程中具有重要作用，且属于可干预的危险因素。本文系统综述近年来不同膳食模式与胆石症发生风险的研究进展，并从炎症反应、氧化应激、肠道微生态、胰岛素抵抗及肝脏代谢方面总结其潜在作用机制，以期为胆石症的膳食预防及营养干预提供依据。
Abstract: Gallstone disease is a common chronic digestive disorder whose onset and progression are closely linked to genetic and various environmental factors. Numerous epidemiological studies have shown that dietary factors play a significant role in the formation of gallstones and constitute modifiable risk factors. This systematic review summarizes recent research on the association between different dietary patterns and the risk of gallstone disease. It also outlines potential mechanisms of action, including inflammatory responses, oxidative stress, gut microbiota, insulin resistance, and hepatic metabolism, with the aim of providing a basis for dietary prevention and nutritional interventions for gallstone disease.
文章引用：郎哲涛, 王二辉. 膳食模式与胆石症关联的研究进展[J]. 临床医学进展, 2026, 16(6): 1265-1271. https://doi.org/10.12677/acm.2026.1662335

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