麻荆止咳颗粒治疗风痰阻肺型咳嗽的效果观察

Observation on the Therapeutic Effect of Ma Jing Zhi Ke Granules in Treating Cough of Wind-Phlegm Obstructing the Lung Type

摘要: 目的：探讨麻荆止咳颗粒治疗风痰阻肺型咳嗽的临床疗效。方法：选取本院2024年1月~2025年6月诊断风痰阻肺型咳嗽的患者122例，采用随机分组方式分为两组：一周治疗组85例、一月治疗组37例，两组均在给予抗感染、止咳化痰等常规西药基础治疗上，联合麻荆止咳颗粒口服。比较两组治疗前后临床疗效、中医症候积分、炎症指标情况。结果：一周治疗组总有效率88.24% (75/85)，一月治疗组总有效率91.89% (34/37)。一周治疗组与一月治疗组治疗后咳嗽、咯痰症候积分均小于治疗前(P < 0.05)。一周治疗组治疗后血WBC、NC、NE%、LY%、NC/LC水平均较治疗前下降(P < 0.05)；一月治疗组血CRP水平较治疗前下降(P < 0.05)。结论：西药基础上加用麻荆止咳颗粒对于炎症指标及症候改善均有疗效，其中延长治疗周期可提升风痰阻肺型咳嗽的治疗效果，改善患者症状。

Abstract: Objective: To explore the clinical efficacy of Ma Jing Zhi Ke Granules in the treatment of cough due to wind-phlegm obstructing the lung. Methods: A total of 122 patients diagnosed with cough due to wind-phlegm obstructing the lung in our hospital from January 2024 to June 2025 were selected and randomly divided into two groups: the one-week treatment group (85 cases)and the one-month treatment group (37 cases). Both groups were treated with conventional Western medicine, such as anti-infection and cough suppression and expectoration, and were additionally administered Ma Jing Zhi Ke Granules orally. The clinical efficacy, TCM syndrome scores, and inflammatory indicators before and after treatment were compared between the two groups. Results: The total effective rate of the one-week treatment group was 88.24% (75/85), and that of the one-month treatment group was 91.89% (34/37). The cough and expectoration syndrome scores of both groups after treatment were lower than those before treatment (P < 0.05). The levels of blood WBC, NC, NE%, LY%, and NC/LC in the one-week treatment group decreased after treatment compared with those before treatment (P < 0.05); the CRP level in the one-month treatment group decreased after treatment compared with that before treatment (P < 0.05). Conclusion: The addition of Ma Jing Zhi Ke Granules to conventional Western medicine has therapeutic effects on inflammatory indicators and syndrome improvement. Extending the treatment period can enhance the therapeutic effect on cough due to wind-phlegm obstructing the lung and improve the symptoms of patients.