勃起功能障碍：冠状动脉疾病的 “前哨信号”
Erectile Dysfunction: A “Sentinel Signal” for Coronary Artery Disease
DOI: 10.12677/acm.2026.1662340, PDF,   
作者: 徐 昊：西安医学院第一附属医院全科医学院，陕西 西安；严琴琴*：西安医学院临床医学院，陕西 西安
关键词: 勃起功能障碍；冠状动脉疾病；心血管风险；预警信号；Erectile Dysfunction； Coronary Artery Disease； Cardiovascular Risk； Warning Sign
摘要: 勃起功能障碍(ED)与冠状动脉疾病(CAD)同源，均为血管内皮功能障碍与动脉粥样硬化在不同靶器官的表现。动脉尺寸假说认为，阴茎动脉更细，病变更早，故ED常较CAD症状提前2~5年出现，是心血管事件的独立预警信号。流行病学显示，两者互为高风险因素：CAD患者ED高发，ED患者主要不良心血管事件风险显著上升。临床应推行“心–性同治”，将ED纳入心血管风险评估，实现早期预警与协同防治。
Abstract: Erectile Dysfunction (ED) and Coronary Artery Disease (CAD) share a common origin, both representing vascular endothelial dysfunction and atherosclerosis manifesting in different target organs. The penile artery size hypothesis posits that the smaller diameter of the penile artery predisposes it to earlier pathological changes, which explains why ED typically precedes CAD symptoms by 2~5 years, serving as an independent sentinel marker of cardiovascular events. Epidemiological evidence confirms a bidirectional relationship: CAD patients have a high prevalence of ED, and men with ED face a significantly elevated risk of major adverse cardiovascular events. In clinical practice, a “cardio-sexual” management approach should be adopted, integrating ED assessment into cardiovascular risk evaluation to enable early warning and collaborative prevention.
文章引用：徐昊, 严琴琴. 勃起功能障碍：冠状动脉疾病的 “前哨信号”[J]. 临床医学进展, 2026, 16(6): 1301-1306. https://doi.org/10.12677/acm.2026.1662340

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