黄色肉芽肿性胆囊炎诊疗的研究进展

Research Progress on the Diagnosis and Treatment of Xanthogranulomatous Cholecystitis

摘要: 黄色肉芽肿性胆囊炎(Xanthogranulomatous Cholecystitis, XGC)是一种以胆囊慢性炎症为基础并伴有黄色肉芽肿形成的破坏性炎症病变。其发病机制不明确，影像学检查的特征性表现不明显，单一检查手段无法满足诊断需要，且与胆囊癌(Gallbladder Cancer, GBC)鉴别困难，极易造成漏诊和误诊。一旦确诊或怀疑为XGC应积极手术治疗，但手术方式的正确选择与实施存在难度。提高对XGC的认识，采用多种检查方法联合应用，紧密结合临床，争取早诊断、早手术治疗已成为临床共识。

Abstract: Xanthogranulomatous Cholecystitis (XGC) is a destructive inflammatory lesion based on chronic cholecystic inflammation accompanied by the formation of xanthogranulomas. Its pathogenesis remains unclear, with no obvious characteristic manifestations on imaging examinations. A single examination method cannot meet the diagnostic requirements, and it is difficult to differentiate from Gallbladder Cancer (GBC), which frequently leads to missed diagnosis and misdiagnosis. Once diagnosed or suspected of XGC, active surgical treatment should be performed, yet the correct selection and implementation of surgical procedures are challenging. It has become a clinical consensus to improve the understanding of XGC, adopt a combination of multiple examination methods, closely integrate with clinical manifestations, and strive for early diagnosis and early surgical intervention.