Hp感染、HbA1c水平与结直肠息肉相关性 研究进展
Progress of Research on Correlation between Helicobacter pylori Infection, HbA1c Levels and Colorectal Polyps
DOI: 10.12677/acm.2026.1662377, PDF,   
作者: 杨 群：内蒙古民族大学第二临床医学院，内蒙古 牙克石；郑 洁, 曹金恒*：内蒙古林业总医院消化内镜中心，内蒙古 牙克石
关键词: 幽门螺杆菌；糖化血红蛋白；结直肠息肉；糖尿病；结直肠癌；Helicobacter pylori； Glycated Hemoglobin； Colorectal Polyps； Diabetes； Colorectal Cancer
摘要: 近年来，幽门螺杆菌(Helicobacter pylori, Hp)感染、糖化血红蛋白(HbA1c)水平与结直肠息肉发生发展的关系引起了广泛关注。多项流行病学调查表明，在Hp感染人群中，结直肠息肉的患病率显著增加。同时，糖尿病或糖代谢异常患者的结直肠息肉发生率也有明显上升趋势。部分研究指出，Hp感染和HbA1c水平升高可能协同作用，进一步增加结直肠息肉的风险。然而，现有研究对Hp感染、HbA1c水平与结直肠息肉的相关性仍存在一定差异，其潜在的病理生理机制尚未完全阐明。因此，本文系统梳理了该领域最新研究进展，重点探讨Hp感染、HbA1c水平与结直肠息肉之间的潜在关联，以期为结直肠息肉的早期预防与干预提供一定参考依据。
Abstract: In recent years, the relationship between Helicobacter pylori (Hp) infection, glycated hemoglobin (HbA1c) levels, and the development of colorectal polyps has attracted extensive attention. Multiple epidemiological investigations have shown that the prevalence of colorectal polyps is significantly increased in populations with Hp infection. Concurrently, the incidence of colorectal polyps in patients with diabetes or abnormal glucose metabolism also shows a notable upward trend. Some studies have indicated that Hp infection and elevated HbA1c levels may act synergistically to further increase the risk of colorectal polyps. However, existing studies still exhibit certain discrepancies regarding the associations among Hp infection, HbA1c levels, and colorectal polyps, and the underlying pathophysiological mechanisms have not yet been fully elucidated. Therefore, this article systematically reviews the latest research progress in this field, with a focus on exploring the potential associations among Hp infection, HbA1c levels, and colorectal polyps, aiming to provide a reference for the early prevention and intervention of colorectal polyps.
文章引用：杨群, 郑洁, 曹金恒. Hp感染、HbA1c水平与结直肠息肉相关性 研究进展[J]. 临床医学进展, 2026, 16(6): 1637-1644. https://doi.org/10.12677/acm.2026.1662377

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