CT联合深度学习技术在腹部脂肪定量中的 研究进展
Research Advances in CT Combined with Deep Learning for Abdominal Fat Quantification
DOI: 10.12677/acm.2026.1662437, PDF,   
作者: 李荣荣, 陈海洋, 王鸿轩, 姬 明, 高春愿*:临潼康复疗养中心医学影像科,陕西 西安;张 悦:核工业417医院检验科,陕西 西安
关键词: 腹部脂肪CT深度学习Abdominal Fat CT Deep Learning
摘要: 随着代谢性疾病负担日益加重以及对肿瘤风险预测指标的重视,腹部脂肪尤其是内脏脂肪组织和皮下脂肪组织的精准量化已成为疾病风险预测与个体化干预的关键指标。传统CT测量方法受限于主观性强、效率低下和可重复性差等问题,难以满足临床对高通量和自动化脂肪参数提取的需求。近年来,深度学习模型与CT的结合,实现了CT图像中腹部脂肪组织的高精度分割与测量,并将腹部脂肪作为代谢性疾病和肿瘤的独立影像生物标志物。本文就CT联合深度学习技术在腹部脂肪测量中的进展进行综述。
Abstract: With the increasing burden of metabolic diseases and the growing emphasis on tumor risk prediction indicators, the accurate quantification of abdominal fat, especially visceral adipose tissue and subcutaneous adipose tissue, has become a key indicator for disease risk prediction and individualized intervention. Traditional CT measurement methods are limited by strong subjectivity and low efficiency and poor reproducibility, making it difficult to meet clinical demands for high-throughput, automated extraction of fat parameters. In recent years, the combination of deep learning models and CT has achieved high-precision segmentation and measurement of abdominal adipose tissue in CT images, and has established abdominal fat as an independent imaging biomarker for metabolic diseases and tumors. This article reviews the research progress of CT combined with deep learning technology in abdominal fat measurement.
文章引用:李荣荣, 陈海洋, 王鸿轩, 姬明, 张悦, 高春愿. CT联合深度学习技术在腹部脂肪定量中的 研究进展[J]. 临床医学进展, 2026, 16(6): 2168-2176. https://doi.org/10.12677/acm.2026.1662437

参考文献

[1] Zhou, H., Li, T., Li, J., Zhuang, X. and Yang, J. (2024) The Association between Visceral Adiposity Index and Risk of Type 2 Diabetes Mellitus. Scientific Reports, 14, Article No. 16634. [Google Scholar] [CrossRef] [PubMed]
[2] Shuster, A., Patlas, M., Pinthus, J.H. and Mourtzakis, M. (2012) The Clinical Importance of Visceral Adiposity: A Critical Review of Methods for Visceral Adipose Tissue Analysis. The British Journal of Radiology, 85, 1-10. [Google Scholar] [CrossRef] [PubMed]
[3] Kandi, S.R., Khera, R., Rajagopalan, S. and Neeland, I.J. (2025) AI in Adipose Imaging: Revolutionizing Visceral Adipose Tissue, Ectopic Fat, and Cardiovascular Risk Assessment. Current Atherosclerosis Reports, 27, Article No. 101. [Google Scholar] [CrossRef
[4] Lee, M., Wu, Y. and Fried, S.K. (2013) Adipose Tissue Heterogeneity: Implication of Depot Differences in Adipose Tissue for Obesity Complications. Molecular Aspects of Medicine, 34, 1-11. [Google Scholar] [CrossRef] [PubMed]
[5] Parikh, A.M., Coletta, A.M., Yu, Z.H., Rauch, G.M., Cheung, J.P., Court, L.E., et al. (2017) Development and Validation of a Rapid and Robust Method to Determine Visceral Adipose Tissue Volume Using Computed Tomography Images. PLOS ONE, 12, e0183515. [Google Scholar] [CrossRef] [PubMed]
[6] van Dijk, D.P.J., Volmer, L.F., Brecheisen, R., et al. (2024) External Validation of a Deep Learning Model for Automatic Segmentation of Skeletal Muscle and Adipose Tissue on Abdominal CT Images. British Journal of Radiology, 97, 2015-2023.
[7] Lee, Y.S., Hong, N., Witanto, J.N., Choi, Y.R., Park, J., Decazes, P., et al. (2021) Deep Neural Network for Automatic Volumetric Segmentation of Whole-Body CT Images for Body Composition Assessment. Clinical Nutrition, 40, 5038-5046. [Google Scholar] [CrossRef] [PubMed]
[8] Weston, A.D., Korfiatis, P., Kline, T.L., Philbrick, K.A., Kostandy, P., Sakinis, T., et al. (2019) Automated Abdominal Segmentation of CT Scans for Body Composition Analysis Using Deep Learning. Radiology, 290, 669-679. [Google Scholar] [CrossRef] [PubMed]
[9] Chen, X., Wang, X., Zhang, K., Fung, K., Thai, T.C., Moore, K., et al. (2022) Recent Advances and Clinical Applications of Deep Learning in Medical Image Analysis. Medical Image Analysis, 79, Article 102444. [Google Scholar] [CrossRef] [PubMed]
[10] Zhou, T., Cheng, Q., Lu, H., Li, Q., Zhang, X. and Qiu, S. (2023) Deep Learning Methods for Medical Image Fusion: A Review. Computers in Biology and Medicine, 160, Article 106959. [Google Scholar] [CrossRef] [PubMed]
[11] Anwar, S.M., Majid, M., Qayyum, A., Awais, M., Alnowami, M. and Khan, M.K. (2018) Medical Image Analysis Using Convolutional Neural Networks: A Review. Journal of Medical Systems, 42, Article No. 226. [Google Scholar] [CrossRef] [PubMed]
[12] 付姣慧, 常晓丹, 沙俏丽, 等. 2011年-2020年深度学习用于医学影像学研究文献分析[J]. 中国介入影像与治疗学, 2022, 19(1): 53-57.
[13] Minaee, S., Boykov, Y.Y., Porikli, F., Plaza, A.J., Kehtarnavaz, N. and Terzopoulos, D. (2021) Image Segmentation Using Deep Learning: A Survey. IEEE Transactions on Pattern Analysis and Machine Intelligence, 44, 3523-3542. [Google Scholar] [CrossRef] [PubMed]
[14] Wilting, F.N.H., Douwes, J.P.J., Patel, A., Schreuder, F.H.B.M., Dammers, R., Hannink, G., et al. (2026) Deep Learning-Based Automated Segmentation of Intracerebral Haemorrhage, Intraventricular Haemorrhage and Perihaematomal Oedema on Non-Contrast CT. European Stroke Journal, 11, aakag007. [Google Scholar] [CrossRef
[15] Li, Z., Cai, R., Qin, Y., Liao, X., Wang, E., Wu, X., et al. (2026) Integration of Radiomics, Deep Learning, Transcriptomics, and Metabolomics Reveals Prognostic Risk Stratification and Underlying Biological Mechanisms in Colorectal Cancer. NPJ Precision Oncology, 10, Article No. 155. [Google Scholar] [CrossRef
[16] Popescu, D.-C. and Găman, M.-A. (2025) Artificial Intelligence for Risk Stratification in Diffuse Large B-Cell Lymphoma: A Systematic Review of Classification Models and Predictive Performances. Medical Sciences, 13, Article 280. [Google Scholar] [CrossRef
[17] 孙淑婷, 刘铖枨, 周广茵, 等. 图像分割算法在医学图像中的应用综述[J]. 现代仪器与医疗, 2024, 30(2): 59-68.
[18] Azad, R., Aghdam, E.K., Rauland, A., Jia, Y., Avval, A.H., Bozorgpour, A., et al. (2024) Medical Image Segmentation Review: The Success of U-Net. IEEE Transactions on Pattern Analysis and Machine Intelligence, 46, 10076-10095. [Google Scholar] [CrossRef] [PubMed]
[19] Koitka, S., Kroll, L., Malamutmann, E., Oezcelik, A. and Nensa, F. (2021) Fully Automated Body Composition Analysis in Routine CT Imaging Using 3D Semantic Segmentation Convolutional Neural Networks. European Radiology, 31, 1795-1804. [Google Scholar] [CrossRef] [PubMed]
[20] Dabiri, S., Popuri, K., Ma, C., Chow, V., Feliciano, E.M.C., Caan, B.J., et al. (2020) Deep Learning Method for Localization and Segmentation of Abdominal CT. Computerized Medical Imaging and Graphics, 85, Article 101776. [Google Scholar] [CrossRef] [PubMed]
[21] Shen, H., He, P., Ren, Y., Huang, Z., Li, S., Wang, G., et al. (2023) A Deep Learning Model Based on the Attention Mechanism for Automatic Segmentation of Abdominal Muscle and Fat for Body Composition Assessment. Quantitative Imaging in Medicine and Surgery, 13, 1384-1398. [Google Scholar] [CrossRef] [PubMed]
[22] Zhang, L., Li, J., Yang, Z., Yan, J., Zhang, L. and Gong, L. (2024) The Development of an Attention Mechanism Enhanced Deep Learning Model and Its Application for Body Composition Assessment with L3 CT Images. Scientific Reports, 14, Article No. 28953. [Google Scholar] [CrossRef] [PubMed]
[23] Zhao, J., An, X., Liu, L., Meng, J., Liu, L. and Mu, Y. (2026) Construction and Validation of a Risk Prediction Model for Metabolic Syndrome: A Cross-Sectional Study Based on Randomized Sampling. Frontiers in Endocrinology, 16, Article 1761342. [Google Scholar] [CrossRef
[24] Isomaa, B., Almgren, P., Tuomi, T., Forsén, B., Lahti, K., Nissén, M., et al. (2001) Cardiovascular Morbidity and Mortality Associated with the Metabolic Syndrome. Diabetes Care, 24, 683-689. [Google Scholar] [CrossRef] [PubMed]
[25] Pickhardt, P.J., Graffy, P.M., Zea, R., Lee, S.J., Liu, J., Sandfort, V., et al. (2021) Utilizing Fully Automated Abdominal CT-Based Biomarkers for Opportunistic Screening for Metabolic Syndrome in Adults without Symptoms. American Journal of Roentgenology, 216, 85-92. [Google Scholar] [CrossRef] [PubMed]
[26] Magudia, K., Bridge, C.P., Bay, C.P., Farah, S., Babic, A., Fintelmann, F.J., et al. (2023) Utility of Normalized Body Composition Areas, Derived from Outpatient Abdominal CT Using a Fully Automated Deep Learning Method, for Predicting Subsequent Cardiovascular Events. American Journal of Roentgenology, 220, 236-244. [Google Scholar] [CrossRef] [PubMed]
[27] Lee, M.H., Zea, R., Garrett, J.W., Summers, R.M. and Pickhardt, P.J. (2024) AI-Based Abdominal CT Measurements of Orthotopic and Ectopic Fat Predict Mortality and Cardiometabolic Disease Risk in Adults. European Radiology, 35, 520-531. [Google Scholar] [CrossRef] [PubMed]
[28] Yan, S.Y., Yang, Y.W., Jiang, X.Y., Hu, S., Su, Y.Y., Yao, H., et al. (2023) Fat Quantification: Imaging Methods and Clinical Applications in Cancer. European Journal of Radiology, 164, Article 110851. [Google Scholar] [CrossRef] [PubMed]
[29] Zhou, H., Tian, L., Wu, Y. and Liu, S. (2024) Computed Tomography-Measured Body Composition Can Predict Long-Term Outcomes for Stage I-III Colorectal Cancer Patients. Frontiers in Oncology, 14, Article ID: 1420917. [Google Scholar] [CrossRef] [PubMed]
[30] Miao, S., Dong, H., Feng, J., Jiang, Y., Sun, M., Liu, Z., et al. (2026) GAST-NET: A Multi-Modal and Multi-Task Deep Learning Framework for Preoperative Prediction of Perineural Invasion and Prognostic Risk in Gastric Cancer. International Journal of Medical Informatics, 212, Article 106348. [Google Scholar] [CrossRef
[31] Mantz, L., Johnson, P.C., Lei, M., Newcomb, R.A., Stacey, J., Yang, D., et al. (2026) Exploratory Association of Muscle and Adipose Tissue Indices with Clinical Outcomes in Aggressive Lymphomas. Cancer, 132, e70313. [Google Scholar] [CrossRef
[32] Lai, Y.-C., Lin, Y.-C., Tai, T.-S., et al. (2026) Deep Learning-Derived CT Body Composition Enhances Survival Risk Stratification beyond the TNM System in Locally Advanced Gastric Cancer: A Multi-Modality Cohort Study. International Journal of Surgery.
[33] Yu, N., Li, J., Cao, D., Chen, X., Yang, D., Jiang, N., et al. (2025) CT-Based Radiomics Signature of Visceral Adipose Tissue for Prediction of Early Recurrence in Patients with NMIBC: A Multicentre Cohort Study. International Journal of Surgery, 111, 9457-9470. [Google Scholar] [CrossRef] [PubMed]
[34] 赵阳. 基于深度学习的三维医学影像分割方法研究[D]: [博士学位论文]. 北京: 中国科学院大学(中国科学院大学工程科学学院), 2024.
[35] Miao, S., Sun, M., Zhang, B., Jiang, Y., Xuan, Q., Wang, G., et al. (2025) Multimodal Deep Learning: Tumor and Visceral Fat Impact on Colorectal Cancer Occult Peritoneal Metastasis. European Radiology, 35, 4522-4532. [Google Scholar] [CrossRef] [PubMed]
[36] 仙同胜, 肖晴. 基于跨模态自监督预训练的U-Net弱监督分割性能提升[J]. 信息记录材料, 2026, 27(7): 45-47.
[37] 张畅. 横向联邦学习性能优化研究及其在医疗健康领域的应用[D]: [博士学位论文]. 北京: 北京科技大学, 2024.