中医药针灸联合生活方式干预对多囊卵巢综合征的临床研究综述

A Review of the Clinical Research on the Combination of Traditional Chinese Medicine Acupuncture and Lifestyle Interventions for Polycystic Ovary Syndrome

摘要: 多囊卵巢综合征(PCOS)是育龄期女性高发的生殖内分泌代谢疾病，以高雄激素血症、持续无排卵、卵巢多囊样改变为核心特征，常伴胰岛素抵抗、肥胖、月经紊乱及不孕，远期易并发糖尿病、心血管疾病、子宫内膜癌等。现代医学以药物、手术为主，但存在副作用、依从性差、复发率高等问题。中医药针灸联合生活方式干预以整体观念、辨证论治为核心，从调节肾–天癸–冲任–胞宫轴、改善胰岛素抵抗、纠正内分泌紊乱、减重调经入手，临床疗效显著、安全性高。本文系统梳理PCOS中西医病因病机、中医药针灸与生活方式干预的作用机制、临床研究进展、联合方案及疗效评价，总结现有研究不足并展望未来方向，为PCOS的中西医结合规范化治疗提供循证依据。

Abstract: Polycystic ovary syndrome (PCOS) is a reproductive endocrine and metabolic disorder that frequently occurs in women of childbearing age. It is characterized by hyperandrogenemia, persistent anovulation, and polycystic changes in the ovaries. It is often accompanied by insulin resistance, obesity, menstrual disorders, and infertility. In the long term, it is prone to complications such as diabetes, cardiovascular diseases, and endometrial cancer. Modern medicine mainly relies on drugs and surgery, but these approaches have problems such as side effects, poor compliance, and high recurrence rates. Traditional Chinese medicine, acupuncture, and lifestyle intervention, based on the holistic concept and syndrome differentiation and treatment, start from regulating the kidney-tiankui-chongren-uterus axis, improving insulin resistance, correcting endocrine disorders, and weight loss and menstrual regulation. They have significant clinical efficacy and high safety. This article systematically reviews the etiology and pathogenesis of PCOS in both Chinese and Western medicine, the mechanism of action of traditional Chinese medicine, acupuncture, and lifestyle intervention, clinical research progress, combined treatment plans, and efficacy evaluation. It summarizes the existing research deficiencies and looks forward to future directions, providing evidence-based support for the standardized treatment of PCOS with a combination of Chinese and Western medicine.