祛风骨痛凝胶膏治疗胸腰椎骨折经皮椎体成形术后下腰痛的临床疗效观察

Clinical Efficacy Observation of Qufeng Gutong Gel Ointment in Treating Low Back Pain after Percutaneous Vertebroplasty for Thoracolumbar Fractures

摘要: 目的：观察祛风骨痛凝胶膏治疗胸腰椎骨折经皮椎体成形术后下腰痛的临床疗效。方法：选取2025年11月至2026年4月收治的胸腰椎骨折经皮椎体成形术后下腰痛患者50例，随机分为对照组和观察组各25例。对照组给予塞来昔布胶囊治疗，观察组在对照组基础上加用祛风骨痛凝胶膏外用。比较两组治疗前后疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、日本骨科协会腰椎评分(JOA)及治疗总有效率。结果：治疗后两组VAS、ODI评分均显著降低(P < 0.05)，JOA评分显著升高(P < 0.05)，且观察组改善程度优于对照组(P < 0.05)。观察组治疗总有效率为96.0%，显著高于对照组的76.0% (P < 0.05)。结论：祛风骨痛凝胶膏联合塞来昔布治疗胸腰椎骨折经皮椎体成形术后下腰痛疗效显著，可有效缓解疼痛、改善腰椎功能，且用药安全性良好，但本研究仍存在样本量、随访周期、评价指标等局限，后续需开展更高质量临床试验进一步验证其远期价值。该联合方案值得临床参考应用。

Abstract: Objective: To observe the clinical efficacy of Qufeng Gutong Gel Ointment in the treatment of low back pain after percutaneous vertebroplasty for thoracolumbar fractures. Methods: A total of 50 patients with low back pain after percutaneous vertebroplasty for thoracolumbar fractures admitted from November 2025 to April 2026 were enrolled and randomly divided into control group and observation group, with 25 cases in each group. The control group was treated with Celecoxib Capsules, while the observation group was additionally given external application of Qufeng Gutong Gel Ointment on the basis of the control group. The Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), Japanese Orthopaedic Association (JOA) lumbar scores before and after treatment, as well as the total clinical effective rate were compared between the two groups. Results: After treatment, the VAS and ODI scores of both groups were significantly decreased (P < 0.05), while JOA scores were obviously increased (P < 0.05); the improvement degree in the observation group was superior to that in the control group (P < 0.05). The total effective rate was 96.0% in the observation group, which was markedly higher than 76.0% in the control group (P < 0.05). Conclusion: Combined application of Qufeng Gutong Gel Ointment and Celecoxib has remarkable curative effect on low back pain after percutaneous vertebroplasty for thoracolumbar fractures. It can effectively relieve pain and improve lumbar spine function with good safety. However, this study has limitations in sample size, follow-up period and evaluation indicators. Further high-quality clinical trials are needed to verify its long-term efficacy. The combined regimen is worthy of clinical application.