中医药治疗脾胃虚寒型胃溃疡的 研究进展

Research Progress on Traditional Chinese Medicine in the Treatment of Gastric Ulcer with Spleen-Stomach Deficiency Cold Pattern

摘要: 胃溃疡是临床高发消化系统疾病，西医以质子泵抑制剂抑酸、抗生素联合根除幽门螺杆菌(Hp)为核心的治疗方案虽短期疗效确切，但存在远期复发率高、不良反应多、肠道菌群失调等局限性。脾胃虚寒型是胃溃疡最常见的中医证型之一，中医药通过整体调节在该证型治疗中展现出独特优势。本文系统梳理近年相关研究，从中药单药、中药复方、中成药、针灸及中医外治法、中西医结合等维度，总结各疗法的临床疗效与作用机制，为脾胃虚寒型胃溃疡的临床规范化治疗提供理论依据与实践参考。

Abstract: Gastric ulcer is a clinically prevalent digestive system disease. Although Western medicine, centered on proton pump inhibitors for acid suppression and antibiotic-based combination therapy for Helicobacter pylori (Hp) eradication, yields definitive short-term efficacy, it is limited by high long-term recurrence rates, frequent adverse reactions, and gut microbiota dysbiosis. The spleen-stomach deficiency-cold pattern represents one of the most common Traditional Chinese Medicine (TCM) syndromes in gastric ulcer cases. TCM demonstrates unique advantages in treating this pattern through holistic regulation. This paper systematically reviews recent relevant studies, summarizing the clinical efficacy and mechanisms of various therapies, including single TCM herbs, TCM formulas, Chinese patent medicines, acupuncture and external therapies, as well as integrated Chinese and Western medicine approaches, to provide a theoretical basis and practical references for the standardized clinical management of gastric ulcer with spleen-stomach deficiency-cold pattern.