基于《黄帝内经》探讨情志因素对银屑病的影响

Exploring the Influence of Emotional Factors on Psoriasis Based on the Huangdi Neijing

摘要: 目的：银屑病是一种临床常见的以红斑，鳞屑，瘙痒等为主要症状的慢性复发性皮肤病，在临床上观察到银屑病的严重程度与情志因素邮寄的关系，本研究旨在观察银屑病的严重程度与情志因素的关系。方法：采集100名临床患者的数据通过统计学分析银屑病严重程度与情志因素的关系，主要疗效指标包括银屑病皮损面积和严重指数评分(PASI)、广泛焦虑量表7项(GAD-7)、抑郁筛查量表9项(PHQ-9)以及生活质量指数(DLQI)。结果：银屑病的皮损面积及严重指数(PASI)及生活质量(DLQI)与焦虑程度及抑郁程度呈明显正相关性(p < 0.005)。结论表明银屑病的严重程度及银屑病患者的生活质量与患者的抑郁及焦虑程度呈明显的正相关性。

Abstract: Objective: Psoriasis is a chronic recurrent dermatosis characterized clinically by erythema, scaling, and pruritus as primary symptoms. Clinical observations have demonstrated a correlation between the severity of psoriasis and emotional factors; this study aimed to investigate this relationship. Methods: Data from 100 clinical patients were collected, and statistical analysis was performed to examine the association between psoriasis severity and emotional factors. Key efficacy indicators included psoriatic lesion area, Psoriasis Severity Index (PASI), Generalized Anxiety Disorder-7 Items Scale (GAD-7), Depression Screening Questionnaire-9 Items Scale (PHQ-9), and Disease-Life Quality Index (DLQI). Results: Psoriatic lesion area, PASI score, and DLQI scores showed significant positive correlations with anxiety and depression levels (p < 0.005). The conclusions indicate that psoriasis severity and patients’ quality of life are markedly positively correlated with levels of depression and anxiety.