妊娠相关卒中：危险因素及病理生理机制研究进展
Pregnancy Associated Stroke: Research Advances in Risk Factors and Pathophysiological Mechanisms
DOI: 10.12677/acm.2026.1672679, PDF,    科研立项经费支持
作者: 李 琳*, 任宏生#：山东第一医科大学附属省立医院重症医学科，山东 济南；楚玉峰#：山东第一医科大学附属省立医院神经内科重症监护室，山东 济南
关键词: 妊娠相关卒中；危险因素；病理生理机制；Pregnancy Associated Stroke； Risk Factors； Pathophysiological Mechanisms
摘要: 妊娠相关卒中是一种罕见而危害严重的妊娠并发症。妊娠期间的血流动力学改变、凝血功能激活以及子痫前期等病理状态均可增加卒中发生风险。其危险因素可分为妊娠特异性和非特异性两类：前者主要包括妊娠期高血压疾病、子痫前期、凝血与纤溶系统变化、血流动力学负荷及脂代谢紊乱等；后者则涉及剖宫产、多产次、脑血管结构异常以及高龄等因素。本文围绕妊娠相关卒中的流行病学特征、妊娠危险因素及其病理生理机制进行综述，以期为该疾病的早期预防和精准治疗提供理论依据与研究思路。
Abstract: Pregnancy associated stroke is a rare but serious complication of pregnancy. Changes in hemodynamics, activation of coagulation function, and pathological conditions such as preeclampsia during pregnancy can all increase the risk of stroke. The risk factors can be divided into two categories: pregnancy specific and non-specific. The former mainly includes gestational hypertension, preeclampsia, changes in coagulation and fibrinolysis systems, hemodynamic burden, and lipid metabolism disorders. The latter involves factors such as cesarean section, multiple pregnancies, abnormal cerebrovascular structure, and advanced age. This article reviews the epidemiological characteristics, pregnancy risk factors, and pathophysiological mechanisms of pregnancy related stroke, in order to provide theoretical basis and research ideas for early prevention and precise treatment of this disease.
文章引用：李琳, 任宏生, 楚玉峰. 妊娠相关卒中：危险因素及病理生理机制研究进展[J]. 临床医学进展, 2026, 16(7): 1580-1590. https://doi.org/10.12677/acm.2026.1672679

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