经食管超声心动图检查(TEE)患者中瑞马唑仑应用效果研究

Study on the Efficacy of Remimazolam in Patients Undergoing Transesophageal Echocardiography (TEE)

摘要: 目的：探讨瑞马唑仑在经食管超声心动图检查(Transesophageal Echocardiography, TEE)患者中的临床应用效果。方法：运用随机数字表法将2025年01月至2026年02月内江市第一人民医院收治的78例需行TEE检查的患者均分为两组，每组纳入39例患者，对比组在检查前运用丙泊酚开展镇静干预，研究组则使用瑞马唑仑开展镇静，对比两组镇静相关不良反应发生情况、生命体征波动情况、检查完成情况、镇静效果4类核心观察指标。结果：研究组镇静相关不良反应发生率低于对比组(P < 0.05)；研究组患者心率、血压波动幅度小于对比组(P < 0.05)；研究组患者的整体检查完成率高于对比组(P < 0.05)；研究组镇静效果优于对比组(P < 0.05)。结论：将瑞马唑仑应用于TEE检查患者，可减少其镇静相关不适反应的出现，维持检查全程生命体征处于相对平稳的状态，提升镇静效果和检查完成率。

Abstract: Objective: To investigate the clinical efficacy of remimazolam for sedation in patients undergoing transesophageal echocardiography (TEE). Methods: A total of 78 patients scheduled for TEE examination admitted to the First People’s Hospital of Neijiang from January 2025 to February 2026 were equally divided into two groups via the random number table method, with 39 patients in each group. The control group received propofol for sedation before examination, while the study group was administered remimazolam for sedation. Four core observation indicators were compared between the two groups: incidence of sedation-related adverse reactions, fluctuation of vital signs, examination completion rate, and sedative efficacy. Results: The incidence of sedation-related adverse reactions in the study group was lower than that in the control group (P < 0.05); the fluctuation ranges of heart rate and blood pressure in the study group were smaller than those in the control group (P < 0.05); the overall examination completion rate of the study group was higher than that of the control group (P < 0.05); the sedative efficacy of the study group was superior to that of the control group (P < 0.05). Conclusion: The application of remimazolam in patients receiving TEE examination can reduce the occurrence of sedation-related adverse reactions, maintain relatively stable vital signs throughout the examination process, and improve sedative efficacy and examination completion rate.