硝基烯参与构建四氢噻吩并喹啉酮的综合实验教学研究：实践与反思

Comprehensive Experimental Teaching of Tetrahydrothienoquinolinone Construction via Nitroalkenes: Practice and Reflection

摘要: 本文将一项真实的合成研究课题——“硝基烯参与构建四氢噻吩并喹啉酮”——转化为本科生的科研训练内容，并从教师视角记录了学生在完整科研流程中的学习体验。实践表明：学生在认知上从“按步骤做”转向“追问为什么”，在操作上从“机械执行”转向“基于信息做决策”，在态度上从“害怕失败”转向“分析失败”。真实的研究情境比任何模拟练习都更能激发深度理解。本文同时反思了实践中的不足，并提出改进方向，为有机化学综合实验教学改革提供一种可参考的路径。

Abstract: This paper transforms a real synthetic research project-the construction of tetrahydrothienoquinolinone via nitroalkenes-into an undergraduate research training experience, and documents students’ learning experiences throughout the complete research process from the instructor’s perspective. The practice reveals that students transitioned cognitively from “following procedures” to “asking why”, operationally from “mechanical execution” to “decision-making based on information”, and attitudinally from “fear of failure” to “analysis of failure”. Authentic research contexts stimulate deeper understanding more effectively than any simulated exercise. This paper also reflects on the limitations of the current practice and proposes directions for improvement, offering a referable pathway for the reform of comprehensive organic chemistry laboratory teaching.