基于文献计量学对国内近20年紫花地丁的研究热点的可视化分析

A Bibliometric and Visual Analysis of Research Hotspots on Viola yedoensis in China over the Past Two Decades

摘要: 目的：基于CiteSpace文献计量学方法，对国内近20年(2005年~2025年)关于紫花地丁研究现状的分析并预测未来的研究热点和发展趋势。方法：分别从中国知网数据库、万方数据库、维普生物医学数据库中收集中药紫花地丁研究文献，并导入NoteExpress中进行查重和人工筛选去重，再利用Excel、CiteSpace软件对有效文献的发文量、发文作者、发文机构、高频关键词等进行可视化分析。结果：共检索到有效文献409篇，发文量最多的作者是李巧峡、董小萍、陈胡兰，发文量最多的机构是西北师范大学生命科学学院，高频关键词与聚类分析结果表明，研究热点围绕质量控制(指纹图谱)、生物活性(抑菌、抗氧化、抗炎等)，临床应用(凉血消肿、疗疮)、研究方向从基础研究逐步向临床应用拓展。结论：研究人员对于紫花地丁药材的研究主要集中在质量控制、生物活性、临床应用等方面，不同作者与研究团队之间的关联性较弱，后期可对紫花地丁的研究进行多方位、多学科的交流学习。

Abstract: Objective: Based on the CiteSpace bibliometric method, this study analyzes the current research status of Viola yedoensis in China over the past two decades (2005~2025) and predicts future research hotspots and development trends. Methods: Research literature on Viola yedoensis was collected from the China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Biomedical Database. The retrieved records were imported into NoteExpress for duplicate checking and manual screening. Excel and CiteSpace software were then used to perform visual analysis of valid publications in terms of publication volume, authors, institutions, and high-frequency keywords. Results: A total of 409 valid articles were retrieved. The authors with the highest publication volumes were Li Qiaoxia, Dong Xiaoping, and Chen Hulan. The institution with the highest publication output was the College of Life Sciences, Northwest Normal University. High-frequency keyword and cluster analysis indicated that research hotspots focused on quality control (fingerprint profiling), bioactivities (antibacterial, antioxidant, anti-inflammatory, etc.), and clinical applications (cooling blood, reducing swelling, treating sores). The research direction has gradually shifted from basic research to clinical applications. Conclusion: Research on Viola yedoensis has primarily concentrated on quality control, bioactivities, and clinical applications. The collaboration among different authors and research teams remains relatively weak. Future studies on Viola yedoensis should involve multidisciplinary and multi-faceted exchanges and learning.