认知障碍药物研发的新靶点探索
Exploration of New Targets in Drug Development for Cognitive Impairment
DOI: 10.12677/hjbm.2026.164081, PDF,   
作者: 任红阳:吉林大学化学学院,吉林 长春;祝艺嘉:长春中医药大学中医学院,吉林 长春;赵婉彤, 孙丹丹, 王华敏:长春金赛药业有限责任公司,吉林 长春;王龄鹤:延边大学药学院,吉林 延吉;柳慧哲*:通化医药健康职业学院,吉林 通化
关键词: 认知障碍神经炎症免疫疗法神经保护基因治疗Cognitive Impairment Neuroinflammation Immunotherapy Neuroprotection Gene Therapy
摘要: 认知障碍严重影响患者的生活质量并带来社会和经济负担。目前的治疗主要集中在缓解症状和延缓疾病进展,但疗效有限,无法根治。随着病理机制研究的深入,新的治疗靶点如神经保护、免疫治疗、抗神经炎症和基因治疗等成为药物研发的热点。未来,结合早期诊断、多靶联合治疗、精准医疗和人工智能驱动,药物研发有望显著改善认知功能衰退,延缓疾病进程并提高生活质量。
Abstract: Cognitive impairment severely impact patients’ quality of life and impose significant social and economic burdens. Current treatments mainly focus on alleviating symptoms and delaying disease progression, but their efficacy is limited and cannot cure the condition. With the deepening of research into the pathological mechanisms, new therapeutic targets such as neuroprotection, immunotherapy, anti-neuroinflammation, and gene therapy have become hot topics in drug development. In the future, combining early diagnosis, multi-target combination therapy, precision medicine, and artificial intelligence-driven approaches, drug development is expected to significantly improve cognitive decline, delay disease progression, and enhance quality of life.
文章引用:任红阳, 祝艺嘉, 赵婉彤, 孙丹丹, 王华敏, 王龄鹤, 柳慧哲. 认知障碍药物研发的新靶点探索[J]. 生物医学, 2026, 16(4): 794-803. https://doi.org/10.12677/hjbm.2026.164081

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