成立肿瘤专科化疗小组对化疗患者生活质量、并发症及依从性的影响研究
Impact of Establishing a Specialized Oncology Chemotherapy Team on Quality of Life, Complications, and Treatment Adherence in Chemotherapy Patients
DOI: 10.12677/acm.2026.1682821, PDF,    科研立项经费支持
作者: 郭玉娟*:国药北方医院肿瘤科,内蒙古 包头;尚新蕊#:国药北方医院耳鼻咽喉科,内蒙古 包头
关键词: 肿瘤专科化疗小组;化疗并发症;血管通路管理;护理管理;静脉炎;Specialized Oncology Chemotherapy Team; Chemotherapy Complications; Vascular Access Management; Nursing Management; Phlebitis
摘要: 目的:本研究探讨成立肿瘤专科化疗小组(以下简称“专科小组”)对化疗患者并发症、生活质量及依从性的影响。方法:选取我院肿瘤科2023年1月至12月收治的120例化疗患者,随机分组,将实施常规护理的患者设为对照组(n = 60),将成立专科化疗小组后实施综合干预的患者设为观察组(n = 60)。观察组干预措施包括:组建专科小组、制定标准化操作流程、开展系统化培训(理论授课 + 模拟演练 + 临床跟岗 + 逆向复盘)、实施血管通路五步闭环管理。比较两组患者化疗前后生活质量评分、相关并发症的发生率及化疗后的依从性及满意度的影响。结果:观察组化疗后生活质量评分明显高于对照组(P < 0.05);化疗后并发症静脉炎、恶心呕吐的发生率均显著低于对照组(P < 0.05);观察组化疗后的依从性、满意度评分均显著高于对照组(P < 0.05)。结论:成立肿瘤专科化疗小组并配套系统化培训、血管通路闭环管理能显著降低化疗并发症的发生率及严重程度,提升患者生活质量、依从性及满意度,该模式值得临床推广。
Abstract: Objective: This study investigates the effect of establishing a specialized oncology chemotherapy team (hereinafter referred to as the “specialized team”) on complications, quality of life, and treatment adherence in chemotherapy patients. Methods: A total of 120 chemotherapy patients admitted to the Department of Oncology of our hospital from January to December 2023 were enrolled and randomly divided into two groups. Patients receiving routine nursing care were assigned to the control group (n = 60), while those receiving comprehensive intervention after the establishment of the specialized chemotherapy team were assigned to the observation group (n = 60). Interventions in the observation group included: forming the specialized team, developing standardized operating procedures, implementing systematic training (theoretical lectures + simulation drills + clinical shadowing + reverse debriefing), and applying a five-step closed-loop management protocol for vascular access. The two groups were compared in terms of quality-of-life scores before and after chemotherapy, incidence of related complications, and post-chemotherapy treatment adherence and satisfaction. Results: The post-chemotherapy quality-of-life scores in the observation group were significantly higher than those in the control group (P < 0.05). The incidences of phlebitis and nausea/vomiting after chemotherapy were significantly lower in the observation group than in the control group (P < 0.05). Post-chemotherapy adherence and satisfaction scores were also significantly higher in the observation group compared with the control group (P < 0.05). Conclusion: Establishing a specialized oncology chemotherapy team, along with systematic training and closed-loop vascular access management, can significantly reduce the incidence and severity of chemotherapy-related complications, improve patients’ quality of life, adherence, and satisfaction. This model is worthy of clinical promotion.
文章引用:郭玉娟, 尚新蕊. 成立肿瘤专科化疗小组对化疗患者生活质量、并发症及依从性的影响研究[J]. 临床医学进展, 2026, 16(8): 506-514. https://doi.org/10.12677/acm.2026.1682821

参考文献

[1] 中国临床肿瘤学会(CSCO)肿瘤支持与康复治疗专家委员会, 褚倩, 褚晓源, 等. 中国肿瘤共病防治专家共识(2025版) [J]. 肿瘤防治研究, 2025, 52(11): 879-912.
[2] 中国抗癌协会大肠癌专业委员会, 中华结直肠癌MDT联盟. 中国结直肠癌肝转移MDT临床实践共识: 2021年版[M]. 北京: 人民卫生出版社, 2021.
[3] Ashley, L., Dexter, R., Marshall, F., McKenzie, B., Ryan, M. and Armitage, G. (2011) Improving the Safety of Chemotherapy Administration: An Oncology Nurse-Led Failure Mode and Effects Analysis. Oncology Nursing Forum, 38, E436-E444.
https://doi.org/10.1188/11.onf.e436-e444
[4] Steinberg, H. (2020) Oncology Nurse Coordinators in Clinical Trials-Shaking up the Melanoma Team. Asia-Pacific Journal of Oncology Nursing, 7, 250-254.
https://doi.org/10.4103/apjon.apjon_19_20
[5] 叶琳, 田莉莉, 李爱霞, 等. 基于质量反馈理论的专科护士全程管理模式在预防PICC导管相关性静脉血栓中的应用[J]. 护理实践与研究, 2026, 23(3): 469-474.
[6] 王雅娟, 李玥璐. 肿瘤患者PICC导管相关性血栓的危险因素及预防措施研究进展[J]. 现代临床医学, 2026, 52(3): 217-219+223.
[7] Parreira, S., Burns, K., Moldawer, N., Zomordian, N., Bandali, N., Virdee, K., et al. (2024) The Role of Nurses in the Management of Adverse Events in Patients Receiving First-Line Axitinib Plus Immuno-Oncology Agents for Advanced Renal Cell Carcinoma. Seminars in Oncology Nursing, 40, Article 151545.
https://doi.org/10.1016/j.soncn.2023.151545
[8] 张桢, 冯梅, 刘芳. 阶段性健康教育对乳房良性肿瘤患者心理状态、生活质量的影响[J]. 肿瘤基础与临床, 2025, 38(2): 266-268.
[9] 谭冬梅. 置管专项护理对肿瘤PICC置管患者静脉炎、血栓及微血栓形成的影响[J]. 血栓与止血学, 2016, 22(4): 441-443.
[10] 朱月娥. PICC专科护理小组对预防肿瘤化疗置管患者并发症及提高患者满意度的影响[J]. 护理实践与研究, 2017, 14(20): 139-141.
[11] 陈小敏, 李垚, 夏敏, 等. 基于计划行为理论的运动助推方案在结直肠癌术后辅助化疗病人中的应用[J]. 护理研究, 2026, 40(9): 1448-1457.