血脂变异性与脑小血管病影像学标志物相关性的初步探讨
A Preliminary Study on the Association between Lipid Profile Variability and Imaging Biomarkers of Cerebral Small Vessel Disease
DOI: 10.12677/jcpm.2026.54235, PDF,   
作者: 王亚雯：承德医学院研究生学院，河北 承德；张广玉*：沧州市人民医院神经内科七区，河北 沧州；徐 明：沧州市人民医院心电图室，河北 沧州
关键词: 血脂变异性；脑小血管病；Lipid Variability； Cerebral Small Vessel Disease
摘要: 脑小血管病(Cerebral Small Vessel Disease, CSVD)是累及脑部微小血管的慢性脑血管疾病，其会使患者自理能力下降，严重影响人群健康水平，消耗大量医疗资源，血脂异常是CSVD病公认的危险因素，且有相对广泛的相关报道，但作为能够反映血脂水平在不同时间段的波动变化指标的血脂变异性，尚未得到临床与科研领域的充分关注。本文旨在初步探讨血脂变异性和CSVD的部分影像学标志物的关系，为进一步管理和干预提供参考。
Abstract: Cerebral Small Vessel Disease (CSVD) is a chronic cerebrovascular disorder affecting the microvasculature of the brain. It leads to a decline in patients’ ability to care for themselves, significantly impacts public health, and consumes substantial healthcare resources. Dyslipidemia is a recognized risk factor for CSVD, with relatively extensive reports on its association; however, lipid variability—an indicator reflecting fluctuations in lipid levels over time—has not yet received sufficient attention in clinical and research settings. This study aims to preliminarily explore the relationship between lipid variability and certain imaging biomarkers of CSVD, providing a reference for further management and intervention.
文章引用：王亚雯, 张广玉, 徐明. 血脂变异性与脑小血管病影像学标志物相关性的初步探讨[J]. 临床个性化医学, 2026, 5(4): 165-169. https://doi.org/10.12677/jcpm.2026.54235

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