≤2 cm上尿路结石术后无管化的研究进展
Research Progress on Postoperative Tubeless Management for Upper Urinary Tract Stones ≤ 2 cm
DOI: 10.12677/acm.2026.1682900, PDF,   
作者: 邓文彪*, 朱智科, 赖伟峰, 宋子阳, 李航飞:赣南医科大学第一临床医学院,江西 赣州;王晓宁#:赣南医科大学第一附属医院泌尿外科,江西 赣州
关键词: 上尿路结石;无管化;经皮肾镜取石术;输尿管镜碎石术;加速康复外科;Upper Urinary Tract Calculi; Tubeless; Percutaneous Nephrolithotomy; Ureteroscopy; Enhanced Recovery after Surgery
摘要: 目的:术后引流管留置曾是上尿路结石微创手术的“标准配置”——肾造瘘管与输尿管支架管被视为保障术后引流、预防并发症的“安全网”。然而,随着加速康复外科理念的深入和手术技术的精细化,这一传统正被逐步打破。无管化(tubeless)技术,即在经皮肾镜取石术(PCNL)或输尿管镜碎石术(URS)后选择性省略肾造瘘管和/或输尿管支架,已成为≤2 cm上尿路结石治疗领域的重要发展方向。大量循证医学证据表明,在严格筛选的患者中,无管化手术可显著减轻术后疼痛、缩短住院时间、加速康复,且不增加并发症风险。2025年EAU指南已将其纳入推荐。本文系统综述≤2 cm上尿路结石术后无管化的定义与分类、适应证、临床证据、技术要点、并发症及未来方向,以期为临床实践和后续研究提供参考。
Abstract: Objective: Postoperative drainage has long been considered a “standard configuration” following minimally invasive surgery for upper urinary tract stones—with nephrostomy tubes and ureteral stents serving as a “safety net” to ensure adequate drainage and prevent complications. However, with the deepening adoption of Enhanced Recovery after Surgery (ERAS) principles and refine-ments in surgical techniques, this tradition is being progressively challenged. Tubeless techniques, defined as the selective omission of nephrostomy tubes and/or ureteral stents after percutaneous nephrolithotomy (PCNL) or ureteroscopy (URS), have emerged as a significant trend in the man-agement of upper urinary tract stones ≤ 2 cm. A growing body of evidence-based medical data indi-cates that, in strictly selected patients, tubeless procedures significantly reduce postoperative pain, shorten hospital stays, accelerate recovery, and do not increase the risk of complications. The 2025 European Association of Urology (EAU) Guidelines have formally incorporated this approach into their recommendations. This article provides a systematic review of the definition, classification, indications, clinical evidence, technical essentials, complications, and future directions of postoper-ative tubeless management for upper urinary tract stones ≤ 2 cm, aiming to offer guidance for clin-ical practice and future research.
文章引用:邓文彪, 朱智科, 赖伟峰, 宋子阳, 李航飞, 王晓宁. ≤2 cm上尿路结石术后无管化的研究进展[J]. 临床医学进展, 2026, 16(8): 1249-1255. https://doi.org/10.12677/acm.2026.1682900

参考文献

[1] European Association of Urology (2025) EAU Guidelines on Urolithiasis. EAU.
[2] Fu, X., Hu, W., Deng, W., Jin, W., Zu, X., Zhu, G., et al. (2025) Total Tubeless Percutaneous Nephrolithotomy without Retrograde Insertion of a Ureteral Catheter for the Treatment of Kidney Stone Patients without Hydronephrosis: A Randomized Controlled Trial. International Urology and Nephrology, 57, 759-767.
https://doi.org/10.1007/s11255-024-04252-w
[3] 杨光远, 孙晓松, 乾孝园, 等. 非逆行插管联合部分无管化经皮肾镜取石术的安全性与有效性[J]. 实用医学杂志, 2025, 41(19): 3072-3077.
[4] 黄国华, 苏帅, 张金栋, 等. “无鞘无管”一期输尿管软镜碎石术在治疗长径 ≤ 10 mm输尿管上段结石和肾结石的有效性和安全性研究[J]. 重庆医科大学学报, 2025(4): 444-448.
[5] Palacios-Navas, A.G., Flores-Bravo, Y., Campos-Muñoz, A.J., Calderón-Fernández, A., de la Luz Nevárez-Rivera, M., Cavillo-Ramirez, A., et al. (2025) IP08-32 the Impact of Size: A Systematic Review and Meta-Analysis of Tubeless versus Standard Percutaneous Nephrolithotomy in 2,267 Adult Patients. Journal of Urology, 213, e429.
https://doi.org/10.1097/01.ju.0001109856.11315.1d.32
[6] Tomer, N., Durbhakula, V., Gupta, K., Khargi, R., Gallante, B., Atallah, W.M., et al. (2024) Is Totally Tubeless Percutaneous Nephrolithotomy a Safe and Efficacious Option for Complex Stone Disease? Journal of Clinical Medicine, 13, Article No. 3261.
https://doi.org/10.3390/jcm13113261
[7] Aboelatta, A.S. (2026) Tubeless Ureteroscopy: A Comprehensive Literature Review. Cureus, 18, e109232.
https://doi.org/10.7759/cureus.109232
[8] Gupta, K., Tomer, N., Connors, C., Gong, S., Khargi, R., Gallante, B., et al. (2025) Is Outpatient Totally Tubeless Standard Percutaneous Nephrolithotomy Safe and Efficacious? Journal of Endourology, 39, 336-342.
https://doi.org/10.1089/end.2024.0441
[9] 梅红兵, 吴建挺. 日间无管化经皮肾镜碎石取石术的临床经验总结及可行性分析(“大家泌尿网”观看手术视频) [J]. 现代泌尿外科杂志, 2024, 29(5): 385-387+393.
[10] Deng, G., et al. (2025) Comparison of the Efficacy of Ureteroscopy through a Flexible Vacuum-Assisted Ureteral Access Sheath with Tubeless-Mini Percutaneous Nephrolithotomy for the Treatment of 2-3 cm Renal Calculi. Urology Journal, 22, 225-230.
[11] Zhang, Y., Li, X., Yang, G., Liu, L., Zhang, X. and Li, W. (2025) Therapeutic Experience and Key Techniques of Tubeless Percutaneous Nephrolithotomy. Scientific Reports, 15, Article ID: 1106.
https://doi.org/10.1038/s41598-024-84806-1
[12] Harrison, N.L., Hughes, C. and Somani, B.K. (2024) Is Stent on a String the New Gold Standard for Postureteroscopy Ureteral Drainage? Evidence from a Systematic Review. Journal of Endourology, 38, 159-169.
https://doi.org/10.1089/end.2023.0412