老年膝骨关节炎与衰弱关系的研究进展

doi:10.12677/acm.2026.1682921

期刊菜单

老年膝骨关节炎与衰弱关系的研究进展
Research Progress on the Relationship between Knee Osteoarthritis and Frailty in the Elderly

DOI: 10.12677/acm.2026.1682921, PDF,
作者: 王僖僖, 高变, 史娟^*：延安大学延安医学院，陕西延安
关键词: 老年人；膝骨关节炎；衰弱；双向关联；Elderly People； Knee Osteoarthritis； Weakened； Bidirectional Association

摘要: 衰弱和膝骨关节炎是老年人群中高发且易共存的两大疾病，二者共存会导致患病自理能力下降、负面情绪增加以及家庭负担加重。膝骨关节炎的高发病率以及高致残率是老年医学领域的重点和难点。老年膝骨关节炎及衰弱已被证实存在相关性。但二者共病的相关机制、炎症机制及相关肌肉减少症等缺少系统梳理。本文将系统梳理二者的相互关系、相关炎症和肌少症的共病机制及干预措施。旨在为老年膝骨关节炎合并衰弱的患者提供准确的评估，尽早开展综合干预以此提高患者的自我护理能力、减轻家庭和医疗负担、提高患者生活质量。

Abstract: Frailty and knee osteoarthritis are two common conditions that frequently coexist in the elderly population. Their coexistence leads to a decline in self-care ability, increased negative emotions, and a greater burden on families. The high prevalence and high disability rate of knee osteoarthritis represent key challenges in the field of geriatrics. A correlation between geriatric knee osteoarthritis and frailty has been established. However, there is a lack of systematic analysis regarding the mechanisms underlying their comorbidity, the associated inflammatory processes, and related sarcopenia. This article systematically examines the interrelationship between the two conditions, the mechanisms of comorbidity involving inflammation and sarcopenia, and relevant intervention strategies. The aim is to provide comprehensive assessments and timely, integrated interventions for patients with geriatric knee osteoarthritis and frailty, thereby enhancing their self-care capabilities, alleviating the burden on families and the healthcare system, and improving patients’ quality of life.

文章引用：王僖僖, 高变, 史娟. 老年膝骨关节炎与衰弱关系的研究进展[J]. 临床医学进展, 2026, 16(8): 1442-1450. https://doi.org/10.12677/acm.2026.1682921

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