中医传统运动干预癌因性疲乏的范围综述
A Scoping Review of the Application of Traditional Chinese Medicine Exercise Interventions in Cancer-Related Fatigue
DOI: 10.12677/ns.2026.158276, PDF,   
作者: 陆柳玉, 褚秋桐:广西中医药大学护理学院,广西 南宁;黄华勇*:广西中医药大学第一附属医院,广西 南宁
关键词: 中医传统运动癌因性疲乏范围综述中医护理Traditional Chinese Exercise Cancer-Related Fatigue Scoping Review Traditional Chinese Medicine Nursing
摘要: 目的:归纳中医传统运动在癌因性疲乏(Cancer-Related Fatigue, CRF)患者护理领域的应用效果及不足。方法:系统检索中国知网、维普、万方数据库、PubMed、Cochrane library、Web of Science、SinoMed中有关中医传统运动对癌因性疲乏的研究,检索时间范围设定为从建库至2026年1月15日,并实施汇总操作及后续分析工作。结果:初检获得976篇文献,最终纳入26篇随机对照试验。详细描述了中医传统运动的基本内容,确定其对CRF患者有积极干预效果。其中,14篇研究采用八段锦干预,10篇研究采用太极拳干预,1篇研究采用六字诀干预,1篇研究采用气功干预。研究中运动频率从每周3~7次不等,每次持续15 min以上,总干预时长为1~6个月。结论:中医传统运动可作为癌因性疲乏的非药物干预手段,但干预时间、干预频率存在异质性,未来需要开展大样本、高质量的研究来验证中医传统运动在CRF患者中的应用效果,为临床制定非药物干预方案提供循证依据。
Abstract: Objective: To summarize the application effects and deficiencies of traditional Chinese medicine exercises in the care of patients with cancer-related fatigue (CRF). Methods: A systematic search was conducted in CNKI, VIP, Wanfang Database, PubMed, Cochrane Library, Web of Science, and Sinomed for studies on the effects of traditional Chinese medicine exercises on CRF. The search period was from the establishment of the databases to January 15, 2026. The included literature was screened, summarized, and analyzed. Results: manifest in the commencement of retrieval amounting to 976 scholarly compositions, merely 26 randomized controlled trials were eventually incorporated. The basic contents of traditional Chinese medicine exercises were described in detail, and it was determined that they have positive intervention effects on CRF patients. Among them, 14 studies used Baduanjin intervention, 10 studies used Tai Chi intervention, 1 study used Liuzijue intervention, and 1 study used Qigong intervention. The exercise frequency in the studies ranged from 3 to 7 times per week, each session lasting more than 15 minutes, and the total intervention duration was 1 to 6 months. Conclusion: Traditional Chinese medicine exercises can be used as a non-pharmacological intervention for CRF, but there is heterogeneity in intervention time and frequency. Future studies need to conduct large-sample, high-quality research to verify the application effects of traditional Chinese medicine exercises in CRF patients and provide evidence-based support for the formulation of non-pharmacological intervention plans in clinical practice.
文章引用:陆柳玉, 黄华勇, 褚秋桐. 中医传统运动干预癌因性疲乏的范围综述[J]. 护理学, 2026, 15(8): 319-329. https://doi.org/10.12677/ns.2026.158276

参考文献

[1] Dee, E.C., Wu, J.F., Feliciano, E.J.G., Ting, F.I.L., Willmann, J., Ho, F.D.V., et al. (2025) National Cancer System Characteristics and Global Pan-Cancer Outcomes. JAMA Oncology, 11, 650-654.
https://doi.org/10.1001/jamaoncol.2025.0473
[2] Ahsan, M.J., Kumar, V., Ali, A., Ali, A., Yusuf, M., Ahmad, I., et al. (2025) Design and Synthesis of Newer 5-Aryl-n-(Naphthalen-2-Yl)-1,3,4-Oxadiazol-2-Amine Analogues as Anticancer Agents. Future Medicinal Chemistry, 17, 1143-1154.
https://doi.org/10.1080/17568919.2025.2504335
[3] Zhao, J., Zhan, L., Pang, Y., Shen, S., Huang, J., Zhang, W., et al. (2025) Prevalence and Risk Factors for Cancer-Related Fatigue in Women with Malignant Gynecological Tumors: A Meta-Analysis and Systematic Review. BMC Cancer, 25, Article No. 827.
https://doi.org/10.1186/s12885-025-14210-z
[4] 殷九旭, 李鑫, 周羚玲, 等. 癌因性疲乏的发病机制及中西医治疗研究进展[J/OL]. 中医学报: 1-7.
https://link.cnki.net/urlid/41.1411.R.20250506.1537.002, 2026-07-31.
[5] Wang, Y., Qin, Y., Xu, X., Li, Y., Zhu, X., Yang, G., et al. (2024) Effects of Baduanjin Exercise on Cancer-Related Fatigue in Patients with Prostate Cancer Treated with Androgen Deprivation Therapy in Shanghai, China: A Study Protocol for a Randomised Controlled Trial. BMJ Open, 14, e092363.
https://doi.org/10.1136/bmjopen-2024-092363
[6] Wu, J., Zhang, C., Jing, Z. and Wu, X. (2025) Randomized Controlled Trial Investigating the Effect of a Baduanjin Exercise Plus Nutrition Programme on Cancer-Related Fatigue in Elderly Lung Cancer Patients Receiving Chemotherapy. Experimental Gerontology, 206, Article ID: 112763.
https://doi.org/10.1016/j.exger.2025.112763
[7] 赵宁, 刘戴维, 张静. 坐位八段锦联合专项呼吸训练对肺癌术后化疗患者肺功能及运动耐力的影响[J]. 河北中医, 2024, 46(4): 628-632.
[8] 刘珊珊, 吁佳, 杨菊莲, 等. 八段锦养生操锻炼对肺癌化疗患者癌因性疲乏及生活质量的影响[J]. 云南中医中药杂志, 2021, 42(8): 99-101.
[9] 姜梦媛, 汪敏, 宋长爱. 太极拳对改善晚期肺癌病人癌因性疲乏及睡眠质量的影响[J]. 护理研究, 2013, 27(5): 420-421.
[10] 苏航, 毕鸿雁. 六字诀干预对肺癌患者癌因性疲乏、肺功能及运动耐力的影响[J]. 山东中医杂志, 2024, 43(7): 729-734.
[11] 葛旦红, 申屠婵婵. 太极拳对中晚期肺癌化疗患者癌因性疲乏的疗效及细胞免疫功能的影响[J]. 中国基层医药, 2019, 26(1): 28-32.
[12] Liu, Y., Liang, X., Yang, B., Wu, Y. and Qian, Y. (2024) Impact of Baduanjin Qigong Exercise on Fatigue in Patients with Lung Cancer: A Randomized Controlled Trial. Journal of Palliative Medicine, 27, 1648-1652.
https://doi.org/10.1089/jpm.2024.0194
[13] Zhang, L., Wang, S., Chen, H. and Yuan, A. (2016) Tai Chi Exercise for Cancer-Related Fatigue in Patients with Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Journal of Pain and Symptom Management, 51, 504-511.
https://doi.org/10.1016/j.jpainsymman.2015.11.020
[14] 庄永玲. 八段锦缓解乳腺癌患者癌因性疲乏的研究[D]: [硕士学位论文]. 青岛: 青岛大学, 2021.
[15] 田贞. 渐进八段锦前四式对乳腺癌术后患者睡眠、细胞免疫及疲乏的影响[D]: [硕士学位论文]. 沈阳: 沈阳体育学院, 2022.
[16] 韩琼, 杨柳, 黄双燕, 等. 八式太极拳对乳腺癌患者癌因性疲乏影响的研究[J]. 广西中医药大学学报, 2019, 22(4): 30-34.
[17] 杨柳, 韩琼, 薛辉, 等. 简易太极拳对乳腺癌患者癌因性疲乏疗效观察与炎症因子的影响[J]. 贵州中医药大学学报, 2022, 44(5): 29-34.
[18] 陈英豪. 太极拳锻炼对乳腺癌患者化疗后癌因性疲乏、身体成分和血脂的影响研究[D]: [硕士学位论文]. 武汉: 武汉体育学院, 2021.
[19] Larkey, L., Huberty, J., Pedersen, M. and Weihs, K. (2016) Qigong/Tai Chi Easy for Fatigue in Breast Cancer Survivors: Rationale and Design of a Randomized Clinical Trial. Contemporary Clinical Trials, 50, 222-228.
https://doi.org/10.1016/j.cct.2016.08.002
[20] 修闽宁. 八段锦对肿瘤化疗病人癌因性疲乏的影响[J]. 全科护理, 2015, 13(30): 3012-3014.
[21] 马献珍. 八段锦养生操对肿瘤患者疲乏的影响[J]. 每周文摘·养老周刊, 2023(13): 119-121.
[22] 朱吉颖, 周红蔚. 八段锦治疗肿瘤患者癌因性疲乏的效果观察[J]. 中国社区医师, 2022, 38(1): 144-146.
[23] 纪钰婷, 袁亚萍. 八段锦在癌因性疲乏患者中的应用效果[J]. 医药前沿, 2024, 14(35): 108-110.
[24] Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., et al. (2010) Impact of Medical Qigong on Quality of Life, Fatigue, Mood and Inflammation in Cancer Patients: A Randomized Controlled Trial. Annals of Oncology, 21, 608-614.
https://doi.org/10.1093/annonc/mdp479
[25] 郑丽红, 翁剑飞, 苏榕. 太极拳运动对胃癌术后患者癌因性疲乏及睡眠质量的改善效果评价[J]. 现代医药卫生, 2022, 38(4): 687-690.
[26] 修闽宁, 何燕燕, 高娟, 等. 八段锦运动处方对晚期胃癌患者癌因性疲乏及希望水平的影响[J]. 医药高职教育与现代护理, 2024, 7(6): 465-469.
[27] 许陶, 陈乐, 金春晖, 等. 八段锦对42例胃肠道恶性肿瘤术后康复期患者癌因性疲乏及生活质量的影响[J]. 中医杂志, 2020, 61(10): 881-885.
[28] Lu, Y., Qu, H., Chen, F., Li, X., Cai, L., Chen, S., et al. (2019) Effect of Baduanjin Qigong Exercise on Cancer-Related Fatigue in Patients with Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Oncology Research and Treatment, 42, 431-439.
https://doi.org/10.1159/000501127
[29] McQuade, J.L., Prinsloo, S., Chang, D.Z., Spelman, A., Wei, Q., Basen‐Engquist, K., et al. (2016) Qigong/Tai Chi for Sleep and Fatigue in Prostate Cancer Patients Undergoing Radiotherapy: A Randomized Controlled Trial. Psycho-Oncology, 26, 1936-1943.
https://doi.org/10.1002/pon.4256
[30] 刘岸, 徐佳. 八段锦疗法对宫颈癌术后化疗患者癌因性疲乏的影响[J]. 湖南理工学院学报(自然科学版), 2024, 37(4): 52-55.
[31] 刘倩倩. 八段锦对子宫内膜癌患者癌因性疲乏的影响[D]: [硕士学位论文]. 兰州: 兰州大学, 2023.
[32] Zhou, W., Wan, Y., Chen, Q., Qiu, Y. and Luo, X. (2018) Effects of Tai Chi Exercise on Cancer-Related Fatigue in Patients with Nasopharyngeal Carcinoma Undergoing Chemoradiotherapy: A Randomized Controlled Trial. Journal of Pain and Symptom Management, 55, 737-744.
https://doi.org/10.1016/j.jpainsymman.2017.10.021
[33] 金玉柱, 李婉琳. “打拳原是备身法”: 太极拳“身法”的核心要义解析[J]. 西安体育学院学报, 2024, 41(4): 516-525.
[34] Yuen, M., Ouyang, H.X., Miller, T. and Pang, M.Y.C. (2021) Baduanjin Qigong Improves Balance, Leg Strength, and Mobility in Individuals with Chronic Stroke: A Randomized Controlled Study. Neurorehabilitation and Neural Repair, 35, 444-456.
https://doi.org/10.1177/15459683211005020
[35] 李文涛, 刘阿庆, 张冠, 等. 三焦针灸法对中晚期胃腺癌癌因性疲乏的疗效及对免疫功能的影响[J]. 实用肿瘤杂志, 2023, 38(3): 270-275.
[36] 刘冲, 徐大志, 向彩琼, 等. 基于数据挖掘研究肠癌癌因性疲乏的用药特点研究[J]. 中国现代医生, 2025, 63(17): 52-55.
[37] 杨书贤, 洪禹, 曹丽娟. 癌因性疲乏发病机制及中医药干预研究进展[J]. 南京中医药大学学报, 2025, 41(6): 838-846.
[38] 李婧, 苏钊, 曹文. 基于《金匮要略》虚劳理论探讨癌因性疲乏的治疗[J]. 中医临床研究, 2024, 16(6): 67-70.
[39] 陈辉, 周亚娜. 太极拳锻炼对老年高血压患者血清TNF-α和IL-6水平的影响[J]. 中国老年学杂志, 2012, 32(11): 2361-2362.
[40] McTiernan, A. (2008) Mechanisms Linking Physical Activity with Cancer. Nature Reviews Cancer, 8, 205-211.
https://doi.org/10.1038/nrc2325
[41] 黄墩兵, 林忠华, 姜财, 等. 全身振动训练联合八段锦运动对老年肌少症患者姿势稳定性的影响[J]. 中国康复, 2023, 38(7): 430-433.
[42] 中国抗癌协会肿瘤营养专业委员会, 肿瘤特医食品国家市场监督重点实验室, 团体作者北京肿瘤学会肿瘤缓和医疗专业委员会. 中国恶性肿瘤患者运动治疗专家共识[J]. 肿瘤代谢与营养电子杂志, 2022, 9(3): 298-311.