中药封包联合吗啡治疗晚期肿瘤癌痛临床观察

Clinical Observation on the Combination of Traditional Chinese Medicine Packaging and Morphine in Treating Advanced Tumor Pain

摘要: 目的：观察中药封包联合吗啡注射液治疗肿瘤终末期癌痛的疗效与安全性。方法：选取2025年7月~2026年2月安宁疗护科收治的80例患者随机均分两组，对照组单用吗啡注射液镇痛，试验组加用辩证中药封包外敷，疗程5天，比较两组治疗前后NRS评分、吗啡日均用量、不良反应发生率及镇痛总有效率。结果：两组疼痛评分均下降，试验组改善更明显，吗啡用量更少，镇痛有效率更高，不良反应发生率显著低于对照组。结论：中西医联合镇痛效果确切，可减少吗啡注射液用量，减轻药物不良反应，安全性良好，适用于安宁疗护临床推广。

Abstract: Objective: To evaluate the efficacy and safety of traditional Chinese medicine dressing combined with morphine injection in managing terminal cancer pain. Methods: A total of 80 patients admitted to the palliative care department from July 2025 to February 2026 were randomly divided into two groups. The control group received morphine injection alone for analgesia, while the experimental group additionally received topical application of traditional Chinese medicine dressings based on syndrome differentiation. The treatment course lasted 5 days. Differences in NRS scores, daily morphine dosage, incidence of adverse reactions, and overall analgesic efficacy were compared between the two groups before and after treatment. Results: Pain scores decreased in both groups, with more significant improvement observed in the experimental group. The experimental group required lower morphine doses, demonstrated higher analgesic efficacy, and exhibited significantly lower adverse reaction rates compared to the control group. Conclusion: The combined approach of traditional Chinese and Western medicine demonstrates proven analgesic efficacy, reduces morphine consumption, mitigates adverse drug reactions, and exhibits good safety profile, making it suitable for clinical implementation in palliative care settings.