中医药治疗过敏性紫癜肾炎的研究进展

Research Progress on Traditional Chinese Medicine Treatment of Henoch-Schönlein Purpura Nephritis

摘要: 过敏性紫癜肾炎(HSPN)是临床常见的过敏性紫癜继发的肾小球疾病，目前西医针对本病以激素、免疫抑制剂等药物为主，其存在不良反应风险较高、停药后容易复发等局限性。中医对HSPN的认识较早，治则治法、治疗方式等依据丰富。笔者系统综述近年来中医药治疗HSPN的相关研究发现，当前中医药治疗HSPN的治疗方法以内治法为主，涉及辨证论治、经方加减、自拟方、中成药等，外治法应用较少，以针灸及穴位贴敷为主，中医药治疗本病疗效确切，本文将予以报道。

Abstract: Henoch-Schönlein Purpura Nephritis (HSPN) is a common glomerular disease secondary to Henoch-Schönlein Purpura in clinical practice. Current Western medical treatment mainly relies on corticosteroids and immunosuppressants, which carry high risks of adverse reactions and a high relapse rate after discontinuation. Traditional Chinese Medicine (TCM) has recognized HSPN at an early stage, with rich theoretical foundations in treatment principles and therapeutic approaches. This paper systematically reviews recent research on TCM treatment of HSPN. The findings indicate that current TCM interventions for HSPN are predominantly internal therapies, including syndrome differentiation-based treatment, classical formula modifications, self-formulated prescriptions, and proprietary Chinese medicines. External therapies are less commonly applied, mainly involving acupuncture and acupoint application. TCM demonstrates definite efficacy in treating this condition, and this paper provides a comprehensive report.