CTI在冠心病中的研究进展
Research Progress of CTI in Coronary Heart Disease
DOI: 10.12677/jcpm.2026.54280, PDF,    科研立项经费支持
作者: 邵春雨：承德医学院研究生学院，河北 承德；侯天华*：河北省承德市中心医院心血管内科一病区，河北 承德
关键词: C反应蛋白–甘油三酯–葡萄糖指数；冠心病；炎症；胰岛素抵抗；综述 ；C-Reactive Protein-Triglyceride-Glucose Index； Coronary Heart Disease； Inflammation； Insulin Resistance； Review
摘要: 近年来，冠心病的死亡率呈持续上升趋势，已经严重威胁国民的健康水平和生活质量。冠心病发生与发展的核心病理基础是动脉粥样硬化，这一过程涉及脂质代谢异常、炎症反应、内皮功能障碍等多种机制的共同参与。C反应蛋白–甘油三酯–葡萄糖指数(CTI)是一种整合了C反应蛋白和甘油三酯–葡萄糖指数的新型复合指标，可同时反映系统性炎症与胰岛素抵抗水平。本文从CTI的定义与计算方法、理论基础、与冠心病危险因素的关系及其在冠心病诊断与预后中的临床应用等方面进行综述，以期为冠心病的诊疗提供新的方向。
Abstract: In recent years, the mortality rate of coronary heart disease (CHD) has shown a sustained upward trend, posing a significant threat to public health and quality of life. The core pathological basis underlying the onset and progression of CHD is atherosclerosis, a process involving multiple mechanisms such as abnormal lipid metabolism, inflammatory responses, and endothelial dysfunction. The C-reactive protein-triglyceride-glucose index (CTI) is a novel composite biomarker that integrates both C-reactive protein and the triglyceride-glucose ratio, providing simultaneous assessments of systemic inflammation and insulin resistance levels. This review examines the CTI’s definition, calculation methodology, theoretical foundations, relationship with CHD risk factors, and clinical applications in CHD diagnosis and prognosis, aiming to offer new insights for CHD management.
文章引用：邵春雨, 侯天华. CTI在冠心病中的研究进展[J]. 临床个性化医学, 2026, 5(4): 533-542. https://doi.org/10.12677/jcpm.2026.54280

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