糖耐量减低与动脉粥样硬化相关性的研究进展
The Research Progress about the Correlation of Impaired Glucose Tolerance and Atherosclerosis
DOI: 10.12677/MD.2015.51001, PDF,  被引量   
作者: 王 敏, 曹中朝：内蒙古医科大学附属医院，内蒙古自治区 呼和浩特
关键词: 糖耐量减低；动脉粥样硬化；颈部血管彩超；Impaired Glucose Tolerance； Atherosclerosis； Carotid Duplex Ultrasound
摘要: 糖尿病已确定为动脉粥样硬化的危险因素，但糖尿病前期的糖耐量减低阶段是否已经开始了动脉硬化的进程尚无明确定论。我们对国内外关于糖耐量减低与动脉粥样硬化的相关研究做了综述，旨在明确糖代谢异常病人的动脉粥样硬化起始阶段，了解动脉僵硬度的变化，从而给予针对性的早期防治，以阻止和延缓血管硬化病变的发生和发展。
Abstract: Diabetes has been identified as a risk factor for atherosclerosis, but whether pre-diabetes glucose tolerance has already started the process of atherosclerosis is still not clear. In this paper, the correlation of impaired glucose tolerance and atherosclerosis was reviewed with the aim to un-derstand the initial stage of atherosclerosis and changes of arterial stiffness in glycometabolism abnormalities patients. It will help provide targeted therapy, reduce or delay the occurrence and development of vascular lesions.
文章引用：王敏, 曹中朝. 糖耐量减低与动脉粥样硬化相关性的研究进展[J]. 医学诊断, 2015, 5(1): 1-5. https://dx.doi.org/10.12677/MD.2015.51001

参考文献

[1] 叶任高, 陆再英, 谢毅, 等 (2006) 内科学. 6版, 人民卫生出版社, 北京, 787-808.
[2] 葛均波, 徐永健 (2014) 内科学. 8版, 人民卫生出版社, 北京, 733-752.
[3] 鲍燕, 李觉 (2009) 冠心病患者餐后高血糖异常的研究进展. 中国心血管病研究, 7, 702-704.
[4] Crouse, J.R., Fueberg, C.D., Espeland, M.A., et al. (2007) B-mode ultrasound: A noninvasive method for assessing atherosclerosis. Cardiovascular Medicine, Springer Press, New York, 1783-1796.
[5] Wang, T.J., Nam, B.H., D’Agostino, R.B., et al. (2003) Carotid intima-media thickness is associated with premature parental coronary hear disease: The Framingham Heart Study. Circulation, 108, 572-576.
[6] 韩静, 蔡剑鸣, 蔡幼铨 (2006) 颈动脉粥样硬化的高分辨MRI研究近况. 中国医学影像学杂志, 14, 218-221.
[7] Raitakari, O.T., Trikka, J.O., Laine, H., et al. (2001) Reduced myocardial fiow reserve relates to increased carotid intima-media thickness in healthy young men. Atherosclerosis, 156, 469-475.
[8] Temelkova-Kurktschiev, T., Koehler, C., Leonhardt, W., et al. (1999) Increased intima-media thickness in newly detected type 2 diabetes. Diabetes Care, 22, 333-338.
[9] Wagenknecht, L.E., Agostino, R.B., Haffiner, S.M., et al. (1998) Inpaired glucose to lerance, type 2 diabetes, and carotid wall thickness: The insulin resistance atherosclerosis study. Diabetes Care, 21, 1821-1818.
[10] 杜锦, 智光, 潘长玉, 等 (2006) 颈动脉内中膜厚度与糖代谢异常的关系及影响因素. 中国全科医学, 16, 1328-1331.
[11] Bonora, E., Kiechl, S., Oberhollenzer, F., Egger, G., Bonadonna, R.C., Muggeo, M. and Willeit, J. (2000) Impaired glucose tolerance, type II diabetes mellitus and carotid atherosclerosis: Prospective results from the Bruneck Study. Diabetologia, 43, 156-164.
[12] Haverkate, F., Thompson, S.G., Pyke, S.D., Gallimore, J.R. and Pepys, M.B., For the European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group (1997) Production of C-reactive protein and risk of coronary events in stable and unstable angina. The Lancet, 349, 462-466.
[13] 刘永兵, 张爱伦 (2005) 老年糖耐量低减患者心血管疾病危险因素及其聚集性研究. 新疆医科大学学报, 5, 437- 439.
[14] Kawano, H., Motoyama, T., Hrashima, O., Hirai, N., Miyao, Y., Sakamoto, T., et al. (1999) Hyperglycemia rapidly suppresses flow-mediated endothelium-dependent vasodilation of brachial artery. Journal of the American College of Cardiology, 34, 146-154.
[15] Kozłowska, L., Rydzewski, A., Fiderkiewicz, B., Wasińska-Krawczyk, A., Grzechnik, A. and Rosołowska-Huszcz, D. (2010) Adiponectin, resistin and leptin response to dietary intervention in diabetic nephropathy. Journal of Renal Nutrition, 20, 255-262.
[16] American Diabetes Association (2010) Standards of medical care in diabetes—2010. Diabetes Care, 33, 11-61.