宫颈癌肝转移预后影响因素的研究进展

Research Progress on Prognostic Factors of Hepatic Metastasis from Cervical Cancer

摘要: 宫颈癌是全球女性生殖系统中最常见的恶性肿瘤之一，其发病率和死亡率均位居首位，对女性健康构成严重威胁。宫颈癌肝转移虽属罕见的远处转移事件，但多发生于疾病晚期或治疗后复发阶段，因起病隐匿、进展迅速、治疗难度大、预后极差，成为临床管理中的重点和难点。早期识别高危人群、及时实施个体化干预，对改善宫颈癌肝转移患者的生存结局具有重要临床意义。本文系统回顾近年来相关文献，围绕病理类型、转移病灶特征、肿瘤分期、治疗方式及社会人群因素等方面，归纳并分析影响宫颈癌肝转移患者预后的关键因素，旨在为临床早期诊断与个体化治疗提供参考依据。

Abstract: Cervical cancer is one of the most common malignant tumors of the female reproductive system worldwide, ranking first in both incidence and mortality and posing a serious threat to women’s health. Hepatic metastasis from cervical cancer is a rare form of distant metastasis, which mostly occurs in the advanced stage of the disease or after tumor recurrence. Characterized by insidious onset, rapid progression, difficult treatment and extremely poor prognosis, it has become a major challenge in clinical management. Early identification of high-risk populations and timely implementation of individualized interventions are of great clinical significance for improving the survival outcomes of patients with hepatic metastasis of cervical cancer. By systematically reviewing relevant literature published in recent years, this article summarizes and analyzes the key prognostic factors for such patients from the perspectives of pathological type, metastatic lesion characteristics, tumor stage, treatment modalities and demographic factors, aiming to provide evidence for early clinical diagnosis and individualized treatment.