基于宣通玄府理论探讨小续命汤
Discussion on Xiaoxuming Decoction Based on the Theory of Dredging the Mysterious Pores
DOI: 10.12677/acm.2026.1693056, PDF,   
作者: 向 婷:黑龙江省中医药科学院研究生院,黑龙江 哈尔滨;刘长发*:黑龙江省中医医院,黑龙江 哈尔滨
关键词: 玄府;宣通玄府;小续命汤;Mysterious Pores; Dredging the Mysterious Pores; Xiaoxuming Decoction
摘要: 目的:基于宣通玄府理论探讨小续命汤。方法:梳理玄府理论的源流发展及宣通玄府法的辨证分类体系,结合小续命汤的药物组成与配伍特点,剖析其基于宣通玄府理论的组方思路,并总结该方在多系统疾病中的临床应用规律。结果:玄府为遍布人体周身的微观孔窍,是气血津液、神机升降出入的核心通道,以通利畅达为生理常态,玄府闭塞而为病;宣通玄府法分虚证和实证两大类共14种具体治法;小续命汤以宣通玄府为核心组方思路,全方寒热并用、散收兼顾、通补同施;该方基于宣通玄府理论可拓展应用于神经系统、风湿免疫性、皮肤科、五官科等多系统疾病。结论:小续命汤的组方配伍始终紧扣宣通玄府核心治则,玄府理论为小续命汤的临床拓展应用提供了重要理论支撑。
Abstract: Objective: To discuss Xiaoxuming Decoction from the perspective of the theory of dredging the mysterious pores. Methods: This paper combed the inheritance and development of the mysterious pores theory and the classification of relevant therapies based on syndrome differentiation. The formula design of Xiaoxuming Decoction was analyzed in view of its herbal compatibility, and its clinical application in various systemic diseases was summed up. Results: Mysterious pores are ubiquitous microscopic orifices governing the movement of qi, blood, body fluid and mental activities; obstruction of these orifices causes illnesses. Therapies for dredging mysterious pores fall into deficiency and excess types with 14 specific methods. Centered on dredging the mysterious pores, Xiaoxuming Decoction features combined cold-warm herbs, coordinated dispersion and astringency, and simultaneous unblocking and tonification. It can be widely used in nervous, rheumatic immune, dermatological and otorhinolaryngological diseases. Conclusion: The compatibility of Xiaoxuming Decoction is closely linked with the therapeutic principle of dredging the mysterious pores, and the mysterious pores theory lays a solid theoretical foundation for its expanded clinical use.
文章引用:向婷, 刘长发. 基于宣通玄府理论探讨小续命汤[J]. 临床医学进展, 2026, 16(9): 363-369. https://doi.org/10.12677/acm.2026.1693056

参考文献

[1] 张印生. 孙思邈医学全书[M]. 北京: 中国中医药出版社, 2015: 380.
[2] 黄帝内经·素问[M]. 北京: 人民卫生出版社, 2012.
[3] 何任. 金匮要略校注[M]. 北京: 人民卫生出版社, 1990: 5-7.
[4] 王肯堂. 疡医证治准绳[M]. 北京: 人民卫生出版社, 2014: 266-274.
[5] 王清任. 医林改错[M]. 李天德, 张学文, 整理. 北京: 人民卫生出版社, 2023.
[6] 李杲. 脾胃论[M]. 北京: 人民卫生出版社, 2007.
[7] 张介宾. 景岳全书[M]. 北京: 人民卫生出版社, 1991.
[8] 叶桂. 临证指南医案[M]. 华岫云, 编次. 北京: 人民卫生出版社, 2006.
[9] 龙绘堂. 蠢子医[M]. 北京: 人民卫生出版社, 1993.
[10] 张再康, 盖红肖. 刘完素开通玄府法在诊治疾病中的应用[J]. 中医药学报, 2018, 46(2): 10-16.
[11] Li, X., Wang, P., Zheng, K., Qi, S. and Tang, D. (2023) The Molecular Mechanism of Xiaoxuming Decoction in the Treatment of Ischemic Stroke Based on Network Pharmacology and Molecular Docking. MedComm—Future Medicine, 2, e58.
https://doi.org/10.1002/mef2.58
[12] 刘萱, 侯惠玲, 宋伟鹏, 等. 小续命汤对神经系统疾病的治疗作用及机制研究进展[J]. 药学前沿, 2024, 28(11): 536-549.
[13] 宋曦, 李雯, 赖海燕. 小续命汤对周围型面神经麻痹疗效及神经电生理干预[J]. 中医药临床杂志, 2017, 29(10): 1741-1744.
[14] Wang, M., Yang, Y., Guo, Y., Tan, R., Sheng, Y., Chui, H., et al. (2023) Xiaoxuming Decoction Cutting Formula Reduces LPS-Stimulated Inflammation in BV-2 Cells by Regulating miR-9-5p in Microglia Exosomes. Frontiers in Pharmacology, 14, Article 1183612.
https://doi.org/10.3389/fphar.2023.1183612
[15] Cheng, X., Yang, H., Yang, Y., et al. (2019) Xiao-Xu-Ming Decoction Extract Alleviates LPS-Induced Neuroinflammation Associated with Down-Regulating TLR4/MyD88 Signaling Pathway in Vitro and in Vivo. Journal of Chinese Pharmaceutical Sciences, 28, 88-99. (In Chinese)
[16] 宋子冲. 小续命汤加减联合温针灸治疗急性缺血性脑卒中风痰阻络证的临床观察[D]: [硕士学位论文]. 秦皇岛: 华北理工大学, 2024.
[17] 冯宇昕. 小续命汤治疗风痰瘀阻型中风病(脑梗死)恢复期的临床观察[D]: [硕士学位论文]. 哈尔滨: 黑龙江中医药大学, 2020.
[18] 王荣华. 小续命汤加减治疗中风病痉挛性偏瘫阳虚证临床疗效观察[D]: [硕士学位论文]. 济南: 山东中医药大学, 2015.
[19] 张南峭, 封银曼, 主编. 黄帝内经∙灵枢[M]. 武汉: 湖北科学技术出版社, 2022.