右美托咪定与瑞马唑仑对全麻患者术后睡眠质量影响的研究进展
Research Progress on the Effects of Dexmedetomidine and Remimazolam on Postoperative Sleep Quality in Patients Undergoing General Anesthesia
DOI: 10.12677/acm.2026.1693070, PDF,    科研立项经费支持
作者: 肖 晓, 宋文静：重庆医科大学第五临床学院，重庆；重庆医科大学附属永川医院麻醉科，重庆；税春玲*：重庆医科大学附属永川医院麻醉科，重庆
关键词: 右美托咪定；瑞马唑仑；睡眠质量；作用机制；临床应用；Dexmedetomidine； Remimazolam； Sleep Quality； Mechanisms of Action； Clinical Applications
摘要: 术后睡眠障碍(Postoperative Sleep Disturbances, PSD)是外科手术后常见的并发症之一，是手术后出现的睡眠–觉醒节律紊乱，导致睡眠质量或睡眠行为异常的临床综合征。PSD可引起术后痛觉敏化、术后认知功能下降、术后谵妄、血压波动等不良结局，从而导致术后恢复延迟、住院时间延长。右美托咪定与瑞马唑仑作为目前围术期常见镇静药物，在改善术后睡眠方面均展现出一定价值，本文将围绕二者的作用机制、睡眠调控特点、临床应用等方面，对围术期睡眠质量影响的最新研究进展展开综述。
Abstract: Postoperative sleep disturbance (PSD) is one of the common complications after surgery. It is a clinical syndrome characterized by sleep-wake rhythm disruption that leads to impaired sleep quality or abnormal sleep behavior following an operation. PSD can result in adverse outcomes such as postoperative pain sensitization, postoperative cognitive decline, postoperative delirium, and blood pressure fluctuations, which in turn delay postoperative recovery and prolong hospital stay. Dexmedetomidine and remimazolam, as commonly used sedative agents in the perioperative period, have both shown promise in improving postoperative sleep. This article reviews the latest research progress on their effects on perioperative sleep quality, focusing on their mechanisms of action, sleep-regulatory characteristics, and clinical applications.
文章引用：肖晓, 税春玲, 宋文静. 右美托咪定与瑞马唑仑对全麻患者术后睡眠质量影响的研究进展[J]. 临床医学进展, 2026, 16(9): 473-481. https://doi.org/10.12677/acm.2026.1693070

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